Best Price Buy Raw Material Pure Powder CAS 1134-47-0 Baclofen

• Powder: Yes
• Customized: Customized
• Certification: GMP, ISO 9001, USP, BP
• Suitable for: Adult
• State: Solid
• Purity: >98%
• Model NO.: baclofen
• Name: Baclofen
• CAS: 1134-47-0
• Mf: C10h12clno2
• Shelf Time: 2 Years
• Transport Package: by Air
• Specification: 98%
• Trademark: HNB
• Origin: China
• HS Code: 2902410000
• Production Capacity: 500000

Product Description

Best price buy Raw Material Pure Powder CAS 1134-47-0 Baclofen

Product Name	Baclofen
Appearance	white powder
cas	1134-47-0
Assay	99%
Keywords	Raw Powder Baclofen;Purity Baclofen;Purity Powder Baclofen
Shelf Life	24 months when properly stored
Storage	Keep in a cool, dry, dark location

 

Baclofen powder also known as β-(4-chlorophenyl)-γ-aminobutyric acid (β-(4-chlorophenyl)-GABA), used as a skeletal muscle relaxant. It is primarily used to treat spasticity. It is also used by compounding pharmacies in topical pain creams as a muscle relaxant. It is a GABA receptor agonist, specifically of the GABAB receptors. Its beneficial effects in spasticity result from actions at spinal and supraspinal sites. It is a derivative of γ-aminobutyric acid (GABA).
A beneficial property of baclofen is that tolerance to its muscle-related therapeutic benefits does not seem to occur to a significant degree - baclofen retains its therapeutic anti-spasmodic effects even after many years of continued use. Newer studies, however, indicate that tolerance may develop in some people receiving intrathecal baclofen treatment.

Baclofen is a γ-aminobutyric acid derivative. It is an antispasmodics class drugs acting on the central nervous system, the brain and spinal cord as a skeletal muscle relaxants and sedatives. It take antispasmodic effect by stimulating receptors to inhibit the release of excitatory amino acids such as glutamic acid, aspartic acid and thereby inhibiting the transfer of single and multi-synaptic reflex in central nervous system, brain and spinal cord.
Clinically it has already been used as racemic agent for treating Muscle spasticity since mid-1960s. Recent studies have also found that this product can significantly reduce the symptoms of gastroesophageal reflux and alleviating related symptoms. It can also alleviate the dystonia of children and treat the urination dysfunction caused by central spinal cord injury.

Function

1). Bone muscle spasm caused by multiple sclerosis.
2). For spasms caused by infectious, degenerative, traumatic, tumor or unexplained spinal cord disease, Such as: spastic spinal paralysis, amyotrophic lateral sclerosis, spinal cord cavitation, transverse myomyelitis, traumatic paraplegia or paralysis, spinal cord compression, spinal cord tumors and motor neuron disease.
3). Used for brain-derived muscle spasms, such as: muscle spasms caused by cerebral palsy, infantile cerebral spasm, stroke and cerebral vascular accidents, brain tumors, degenerative encephalopathy, meningitis, and craniocerebral trauma.
4). It can also be used for urinary retention caused by external sphincter.

Function of baclofen

It works by slowing down impulses in the brain that cause seizures. 

Application of baclofen

Application: Used as a skeletal muscle relaxant and tranquilizer for the spinal cord