Aztreonam has the characteristics of weak immunogenicity and less cross allergy with penicillins and cephalosporins, so it can be used to replace aminoglycoside drugs to treat aerobic gram-negative bacterial infections in patients with renal impairment; Under observation, it is used for patients allergic to penicillin and cephalosporin.
1. Urinary tract infections: simple and complex pyelonephritis caused by Escherichia coli, Proteus mirabilis, Pseudomonas aeruginosa, Enterobacter cloacae, Klebsiella odorifera, Citrobacter, Serratia marcescens And recurrent cystitis. 2. Lower respiratory tract infections: Pneumonia and bronchitis caused by Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, Haemophilus influenzae, Proteus mirabilis, Enterobacter and Serratia marcescens.
3. Bloodstream infections: bloodstream infections caused by Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, Proteus mirabilis, Serratia marcescens and Enterobacter.
4. Skin and soft tissue infections: skin and soft tissue infections (including surgical wound infections) caused by Escherichia coli, Proteus mirabilis, Serratia marcescens, Enterobacter, Pseudomonas aeruginosa, Klebsiella pneumoniae, and Citrobacter , Ulcer and burn wound infection).
5. Peritonitis and other abdominal infections: including Escherichia coli, Klebsiella smelly nose, Klebsiella pneumoniae, Enterobacter cloacae, Pseudomonas aeruginosa, Citrobacter, and Serratia marcescens. Often need to be combined with anti-anaerobic drugs such as metronidazole.
6. Reproductive tract infections: Gynecological infections such as Escherichia coli, Klebsiella pneumoniae, Enterobacter (including Enterobacter cloacae), Pseudomonas aeruginosa, Proteus mirabilis, such as endometritis, pelvic inflammatory disease, etc. Need to be combined with anti-anaerobic drugs such as metronidazole
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