Powder: | Yes |
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Customized: | Non-Customized |
Certification: | GMP, HSE, ISO 9001, USP, BP |
Suitable for: | Elderly, Adult |
State: | Solid |
Purity: | >99% |
Samples: |
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Customization: |
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Product Information | |
Other Name | Tacrolimus monohydrate |
Purity | 99% |
Apprearance | White crystalline powder |
Package | 1kg/carton; 25kg/drum |
Payment | Alipay; Western Union; TT |
Shipment | DHL; FedEx, EMS; Air; Sea |
Standard | USP/EP/CP/BP |
Storage | Sealed in dark and dry place |
Shelf Life | 2 Years |
What is Tacrolimus monohydrate? Tacrolimus monohydrate is a macrolide isolated from Streptomyces spp. It has a strong immunosuppressive effect, binding specifically to and inhibiting calmodulin phosphatase activity and inhibiting IL-2 signaling transcription, thereby inhibiting T-cell activation, TNF-α, IL-1β and IL-6 production and T-cell-dependent B-cell proliferation. Compared with cyclosporine, another calmodulin phosphatase inhibitor, tacrolimus inhibits T-cell activation more strongly and has fewer adverse effects. |
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Application & Function Tacrolimus mainly inhibits the synthesis of interleukin-2. It is used for rejection of organ transplants and is more effective in acute rejection reactions. |
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