CAS 74578-69-1 Antibiotic Ceftriaxone Sodium

• Powder: Yes
• Customized: Customized
• Certification: GMP, ISO 9001, USP, BP
• Suitable for: Elderly
• State: White or a Kind of White Crystal Powder
• Purity: >99%
• Model NO.: Ceftriaxone Sodium
• CAS: 74578-69-1
• Mf: C18h17n8nao7s3
• Einecs No.: 277-930-0
• Test Method: HPLC
• Shelf Life: 24 Months
• Storage: Cool Dry Place
• Transport Package: 1kg/Bag, 25kg/Drum
• Specification: Antibiotic ceftriaxone sodium
• Trademark: HNB
• Origin: China
• Production Capacity: 3000kg/Month

Product Description

Name	Ceftriaxone Sodium
CAS	74578-69-1
MF	C18H17N8NaO7S3
Form	white powde
Purity	99%
Grade	Medicine grade

Ceftriaxone sodium as a semi-synthetic third-generation cephalosporins, for most Gram-positive bacteria and-negative bacteria have strong antibacterial activity, antibacterial spectrum, including Pseudomonas aeruginosa, Escherichia coli, Klebsiella pneumoniae, Haemophilus influenzae, bacterial intestinal gas production , Proteus, and Staphylococcus aureus meningitis is so. The drug on β-lactamase stability.

Function

The main clinical infection for susceptible strains of meningitis, pneumonia, skin and soft tissue infections, peritonitis, urinary tract infections, gonorrhea, liver and gallbladder infection, surgical trauma, sepsis, and genital infections. As a treatment for gonorrhea has been first-line drugs.

Application

Ceftriaxone injection is often used (in combination, but not direct, with macrolide and/or
aminoglycoside antibiotics) for the treatment of community-acquired or mild to moderate health care-associated pneumonia. It is also a choice drug for treatment of bacterial meningitis. In pediatrics, it is
commonly used in febrile infants between 4 and 8 weeks of age who are admitted to the hospital to exclude sepsis.


 

Item			Specification	Results
Characters			Appearance:almost white or yellowish, slightly hygroscopic, crystalline powder Solubility:freely soluble in water, sparingly soluble in methanol, very slightly soluble in anhydrous ethanol.	Almost white, slightly hygroscopic, crystalline powder; Solubility: Conform
Identification			1. A. Infrared absorption spectrophotometry, comparison; 2. B. It gives reaction (a) of sodium	Positive
PH			6.0-8.0	7.3
Specific optical rotation			-155°~-170°	-160°
Appearance of solution			It is Clear and not more intensely colored than reference solution Y5 or BY5	Clear,5
Related substances	Any impurity		≤1.0%	0.1%
	Total impurities		≤4.0%	0.4%
Water			≤8.0-11.0%	8.8%
N,N-Dimethylanlline			≤0.0020%	Not detected
2-Ethylhexanoic			≤0.8%	0.002%
Bacterial endotoxins			<0.08IU/mg	<0.08IU/mg
Sterility			Sterile	Sterile
Sub-visible particles		≥10μm	Not more than 2250 particles/g	608 particles/g
		≥25μm	Not more than 225 particles/g	26 particles/g
Assay(based on anhydrous substance)			96.0%-102.0% of C18H16N8Na2O7S3	99.2%
Conclusion			The above results meet the EP8.0th Edition