| Customization: | Available |
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| Powder: | Yes |
| Customized: | Customized |
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| Product Name | S-carboxymethyl-L-cysteine |
| CAS number | 638-23-3 |
| Molecular formula | C5H9NO4S |
| Molecular weight | 179.19 |
| Appearance | white to slightly off-white amorphous powder |
| Melting point | 205-207ºC |
| Flash point | 191.8ºC |
| Relative density | 1.451g/cm3 |
Product Description
Carbocisteine (INN), also called carbocysteine (USAN), is a mucolytic that reduces the viscosity of sputum and so can be used to help relieve the symptoms of chronic obstructive pulmonary disorder (COPD) and bronchiectasis by allowing the sufferer to bring up sputum more easily. Carbocisteine should not be used with antitussives (cough suppressants) or medicines that dry up bronchial secretions.
Carbocisteine is produced by alkylation of cysteine with chloroacetic acid.
Function and Application
An important pharmaceutical raw material; used in the synthesis of a variety of drugs, can reduce the stickiness of respiratory secretions, for the treatment of chronic tracheitis, emphysema, tuberculosis and so on.
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Test Item |
Specification: AJI92 |
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Description |
A white or almost white, crystalline powder, particularly insoluble in water and in alcohol. It dissolves in dilute mineral acids and in dilute solutions of alkali hydroxxides. |
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Identification |
A. It complies with the test for specific optical rotation |
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B. The IR spectrum of the sample is concordant with the spectrum of the reference standard, Carbocisteine CRS |
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C. The principal spot in the chromatogram obtained with the test solution(b) is similar in position,color and size to the principal spot in the chromatogram obtained with the reference solution(a) |
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D. Dark red color is produced, which changes to brown and then to yellow within a few minutes |
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pH |
2.8~3.0 |
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Specific optical rotation[α]D20 |
-32.5° to -35.5°(on dried basis) |
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State of solution (Transmittance) |
Solution S is clear and colourless Not less than 96.0% |
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Nihydrin-positive substances |
Not more than 0.5% |
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Chloride(Cl) |
Not more than 0.15% |
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Sulfate(SO4) |
Not more than 0.030% |
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Heavy metals(Pb) |
Not more than 0.001% |
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Loss on Drying |
Not more than 0.5% |
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Sulfated ash |
Not more than 0.30% |
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Assay |
98.5% ~ 101.0% |
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