Powder: | Yes |
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Customized: | Customized |
Certification: | GMP, HSE, ISO 9001, USP, BP |
Suitable for: | Elderly, Children, Adult |
State: | Powder |
Purity: | >99% |
Samples: |
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Customization: |
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Product Name |
Polaprezinc |
CAS | 107667-60-7 |
Molecular formula |
C9H12N4O3Zn |
Molecular weight |
289.61 |
Grade Standard | Medicine Grade |
Polaprezinc is an orally bioavailable chelate composed of zinc and L-carnosine, with potential gastroprotective, anti-oxidant, anti-ulcer and anti-inflammatory activities. Upon administration, polaprezinc increases the expression of various anti-oxidant enzymes, such as superoxide dismutase 1 (SOD-1), SOD-2, heme oxygenase-1 (HO-1), glutathione S-transferase (GST), glutathione peroxidase (GSH-px), peroxidredoxin-1 (PRDX1; PRXI) and PRXD5 (PRXV) in the gastric mucosa, which protect cells against reactive oxygen species (ROS). In addition, this agent inhibits the activity of the transcription factor nuclear factor-kappaB (NF-kappaB) and reduces the expression of several pro-inflammatory cytokines, such as interleukin (IL) 1beta, IL-6, IL-8, and tumor necrosis factor alpha (TNF-a).
1. NL-carnosine is used toan oxidation resistance.
2. L-carnosine can extend cell life.
3. it can retain body PH balance.
ITEMS
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SPECIFICATIONS
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Appearance
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White or Pale Yellowish White
|
Odor
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Odorless
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Optical Rotation(C=1 0.5NHCl)
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+8°~+9°
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Lead
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2ppm max
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Related Substance
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Not more than 1.0%
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Water
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5% max
|
Carnosine Content
|
76.0-80.0%
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Zinc Content
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21.5-23.0%
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