| Powder: | Yes |
|---|---|
| Customized: | Customized |
| Certification: | ISO 9001, USP, BP |
| State: | White Powder |
| Purity: | >99% |
| CAS: | 60142-96-3 |
| Samples: |
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| Customization: |
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| Product Name | Gabapentin Powder |
| Synonym | 1-(Aminomethyl)cyclohexaneacetic acid |
| Purity | 99%min |
| Appearance | White powder |
| CAS No. | 60142-96-3 |
| EINECS | 262-076-3 |
| Molecular formula | C9H17NO2 |
| Molecular weight | 171.2368 |
Gabapentin is structurally similar to GABA (sc-203053; γ-aminobutyric acid) and is reported in various research studies to increase GABA concentrations within the brain. Gabapentin is also noted to bind to a novel site on voltage-sensitive Ca2+ channels.
Additionally, Gabapentin is reported to demonstrate inhibition of dopamine release from caudate nucleus, preventneuronal cell death, and is antinociceptive.
Gabapentin is an anticonvulsant that is chemically unrelated to any other anticonvulsant or mood regulating medication. Gabapentin received final approval for marketing in the USA on 30 December 1993 and is labeled only for use as an anticonvulsant. It is also widely used to treat individuals suffering from many kinds of pain problems, tremors, restless legs syndrome, hot flashes associated with menopause, and various psychiatric disorders.
Application
Gabapentin is an anticonvulsant that is chemically unrelated to any other anticonvulsant or mood regulating medication. Gabapentin received final approval for marketing in the USA on 30 December 1993 and is labeled only for use as an anticonvulsant. It is also widely used to treat individuals suffering from many kinds of pain problems, tremors, restless legs syndrome, hot flashes associated with menopause, and various psychiatric disorders.
Gabapentin is structurally similar to GABA (sc-203053; -aminobutyric acid) and is reported in various research studies to increase GABA concentrations within the brain. Gabapentin is also noted to bind to a novel site on voltage-sensitive Ca2+ channels.
Additionally, Gabapentin is reported to demonstrate inhibition of dopamine release from caudate nucleus, preventneuronal cell death, and is antinociceptive.
| ITEMS | SPECIFICATIONS | RESULTS |
| DESCRIPTION | WHITE OR OFF-WHITE CRYSTALLINE POWDER | WHITE CRYSTALLINE POWDER |
| IDENTIFICATION | ||
| IR | IR SPECTRUM IS CONSISTENT WITH GABAPENTIN RS | CONFORMS |
| HPLC | CONFORM WITH THE RT OF THE MAJOR PEAK IN HPLC WITH USP GABAPENTIN WRS | CONFORMS |
| PH | 6.5~8.0 | 7.1 |
| WATER | ≤ 0.5% | 0.04% |
| RESIDUE ON IGNITION | ≤ 0.1% | 0.02% |
| LIMIT OF CHLORIDE | ≤ 0.01% | 0.003% |
| HEAVY METALS | ≤ 0.02% | < 0.002% |
| RESIDUAL SOLVENTA | ||
| ETHANOL | ≤ 0.50% | 0.005% |
| RELATED COMPOUNDS | ||
| GABAPENTIN RELATED COMPONENTA A | ≤ 0.10% | 0.01% |
| ANY UNKROWN IMPURITY | ≤ 0.10% | 0.01% |
| TOTAL IMPURITIES | ≤ 0.50% | 0.03% |
| ASSAY | 98.0%~102.0% | 100.6% |
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