85547-56-4 Piperaquine Phosphate

• Powder: Yes
• Customized: Customized
• Certification: GMP, ISO 9001, USP, BP
• State: White Powder
• Purity: >99%
• CAS: 85547-56-4
• Model NO.: Piperaquine phosphate
• Mf: C29h35cl2n6o4p
• MW: 999.56
• Test Method: HPLC UV
• Particle Size: 100% Pass 80 Mesh
• Shelf Life: 24 Months
• Storage: Cool Dry Place
• Transport Package: 1kg/Bag, 25kg/Drum
• Specification: Piperaquine phosphate
• Trademark: HNB
• Origin: China
• Production Capacity: 2000kg/Month

Product Description

Name	Piperaquine phosphate
Brand	Excolla
Molecular Formula	C29H32Cl2N6.4(H3PO4).4(H2O)
Molecular Weight	999.56
CAS Registry Number	4085-31-8

 

Piperaquine is an antimalarial drug, a bisquinoline first made in the 1960s, and used extensively in China and Indochina as prophylaxis and treatment during the next 20 years. Usage declined in the 1980s as piperaquine-resistant strains of P. falciparum arose and artemisinin-based antimalarials became available. However, Chinese scientists have been studying whether piperaquine can still be used therapeutically in combination with artemisinin.

Piperaquine is characterized by slow absorption and a long biological half-life, making it a good partner drug with artemisinin derivatives which are fast acting but have a short biological half-life. 

Item	Specification
Specific rotation	+39.5 to +41.5°
State of solution(transmittance)	Clear 98.0% min.
Chloride[cl]	0.020% max.
Ammonium [NH4]	0.02% max.
Sulfate[SO4]	0.020% max
Iron[Fe]	10ppm max.
Heavy metals [Pb]	10ppm max
Arsenic[As2O3]	1ppm max
Other amino acids	Chromatographically not detectable
Loss on drying	0.20% max.
Residue on ignition[sulfated]	0.10% max.
Assay	99.0% min