Raw Material Powder CAS 73231-34-2 Veterinary Albendazole Florfenicol

• Varieties: Parasite Disease Prevention Medicine
• Component: Animal
• Type: The First Class
• Pharmacodynamic Influential Factors: Animal Species
• Storage Method: Prevent High or LowTemperature
• Veterinary Reg. No.: 09853
• Model NO.: Florfenicol
• Product: Florfenicol
• CAS: 73231-34-2
• Mf: C12h14cl2fno4s
• Transport Package: Drum
• Specification: 99%
• Trademark: HS
• Origin: China
• HS Code: 2904201000
• Production Capacity: 100000

Product Description

product name	Florfenicol	MF	C12H14CL2FNO4S

English Name :Florfenicol
Molecular Formula :C12H14Cl2FNO4S
Specification:50g: 5g (10%)
Loss on Drying:<10%
Appearance:White powder.
Shelf Life:Two years.

Name
Florfenicol Powder (FUDAO)

Ingredients
Florfenicol

Properties
This product is white or almost white powder.
 

Pharmacology
Pharmacodynamics
Florfenicol is a broad-spectrum antibiotic of amide alcohols and is a bacteriostatic agent. It acts by binding to the 50 S subunit of the ribosome to inhibit bacterial protein synthesis. It has strong antibacterial activity against a variety of Gram-positive bacteria and Gram-negative bacteria. Pasteurella hemolyticus, Pasteurella multocida and Actinobacillus pleuropneumoniae are highly sensitive to florfenicol. The antibacterial activity of florfenicol against many microorganisms in vitro is similar to or stronger than that of thiamphenicol. Some bacteria resistant to amide alcohols due to acetylation, such as Escherichia coli and Klebsiella pneumoniae, may still be resistant to fluorobenzene Nico is sensitive. It is mainly used for the bacterial diseases of pigs, chickens and fish caused by sensitive bacteria, such as the respiratory diseases of cattle and pigs caused by Pasteurella hemolyticus, Pasteurella multocida and Actinobacillus pleuropneumoniae. Salmonella caused by typhoid fever and paratyphoid fever, chicken cholera, chicken pullorum, colibacillosis, etc.; fish bacterial sepsis caused by fish pasteurella, vibrio, Staphylococcus aureus, hydrophila, enteritis, etc. Enteritis, red skin disease, etc.

Pharmacokinetics
Florfenicol is absorbed rapidly by oral administration, and the therapeutic concentration can be reached in the blood after about 1 hour, and the peak blood concentration can be reached within 1 to 3 hours. The bioavailability is over 80%. Florfenicol is widely distributed in animals and can penetrate the blood-brain barrier. It is mainly excreted in urine in its original form, and a small amount is excreted in feces.

Medicine interactions
1. Macrolides and lincosamides have the same target of action as this product, both of which are combined with the 50 S subunit of the bacterial ribosome, and can produce mutual antagonism when used in combination.
2. It may antagonize the bactericidal activity of penicillin or aminoglycoside drugs, but it has not been proven in animals.

Function and Use
Amido alcohol antibiotics. Used for bacterial diseases caused by Pasteurella and Escherichia coli.

Usage and Dosage
Based on this product. Oral administration: per 1 kg of body weight, pigs and chickens 0.1 ~ 0.15g, 2 times a day, continuous use for 3 ~ 5 days; fish 50 ~ 75 mg, once a day, continuous use for 3 ~ 5 days.

Adverse reactions
1. This product has a certain immunosuppressive effect when used higher than the recommended dose.
2. It has embryo toxicity, it should be used with caution for livestock during pregnancy and lactation.

Precautions
1. Banned during laying hens.
2. Animals with severely impaired immune function during vaccination period are prohibited.
3. Animals with renal insufficiency need to appropriately reduce the dose or extend the interval between administrations.

Withdrawal period
The pig takes 20 days, the chicken takes 5 days, and the fish takes 375 degree-days.

Specifications
20%

Packaging
500g/bag

Storage
Shading, sealed, and stored in a dry place.

Florfenicol prevents bacteria from growing when it binds to 50S ribosome in the animal. It is an antibiotic used mainly for the treatment of freshwater- and seawater-reared fish diseases associated with Aeromonas, Vibriones, Edwardsiella.

Usage
Dose: 10-15mg/kg body weight/day. Mixed with fish feed. Feed as the sole ration for 3-5 consecutive days.

Precautions
1. At the completion of mixing, the product cannot be stored for a long time.
2. Not for long-term use with megadose.

Storage
Keep container tightly closed. Store in a cool, dry, well-ventilated area.

 

Product Name	Florfenicol
Package	25kg/drum
Quantity	5000kgs
Characteristics	White or off white crystalline powder
Melting point	152.0-156.0ºC
Specific rotation	-16° ~ -19°
PH	4.5~6.5
Chlorides	≤0.02%
Residue on ignition	≤0.1%
Impurity	Individual impurities≤0.5% Total impurities≤1.0%
Heavy Metal	≤20ppm
Fluorine content	≥4.8%
Loss on drying	≤0.5%
Assay	≥98.0%