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Lovastatin can reduce the synthesis of cholesterol and increase the synthesis of low-density lipoprotein receptors, mainly in the liver, resulting in lower blood cholesterol and low-density lipoprotein cholesterol levels. and prevention of coronary heart disease. This product also reduces serum triglyceride levels and increases blood high-density lipoprotein levels. Oral absorption is good, but absorption is reduced by 30% on an empty stomach. This product is extensively metabolized in the liver and hydrolyzed into a variety of metabolites. After long-term treatment, the drug is discontinued, and the effect lasts for 4 to 6 weeks.
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English name Lovastatin CAS No. 75330-75-5 Molecular weight 404.540 Density 1.1±0.1 g/cm3 Boiling point 559.2±50.0 °C at 760 mmHg Molecular formula C24H36O5 Melting point 175°C Flash point 185.3±23.6 °C |