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Epirubicin belongs to the class of antibiotic antitumor drugs. It is an isomer of doxorubicin, and its mechanism of action is to directly intercalate between DNA nucleobase pairs, interfere with the transcription process, prevent the formation of mRNA, and thereby inhibit the synthesis of DNA and RNA. In addition, epirubicin also has an inhibitory effect on topoisomerase II. It is a cell cycle non-specific drug and is effective for a variety of transplanted tumors. Compared with adriamycin, the curative effect is equal or slightly higher, but it is less toxic to the heart.
English name: Epirubicin CAS Number: 56420-45-2 Molecular formula: C27H29NO11 Molecular weight: 543.5193 |