| Customization: | Available |
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| Powder: | Yes |
| Customized: | Customized |
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Name : Cyclophosphamide
Shape : White crystalline powder
1. As an anti-tumor agent, it is used for malignant lymphoma, multiple myeloma, breast cancer, small cell lung cancer, ovarian cancer, neuroblastoma, retinoblastoma, Ewing's sarcoma, soft tissue sarcoma, acute leukemia and chronic lymphocytic leukemia.It is also effective for testicular tumor, head and neck squamous cell cancer, nasopharyngeal cancer, rhabdomyoma and osteosarcoma.At present, it is mostly combined with other anticancer drugs to form chemotherapy regimens.
2. As an immunosuppressant for a variety of autoimmune diseases, such as severe rheumatoid arthritis, systemic lupus erythematosus, nephrotic syndrome in children, multiple granuloma, pemphigus, ulcerative colitis, idiopathic thrombocytopenic purpura, etc.It is also used in organ transplantation for anti-rejection, usually in combination with anti-lymphocytic globulin.
3. This medicine eye drops can be used for pterygium surgery, corneal transplantation after the silkworm corneal ulcer.
Cyclophosphamide (CTX) is a nitrogen-mustard derivative which is hydrolyzed by excessive phosphatase or phosphatase in liver or tumor.It has a broad anti-tumor spectrum and is the first so-called "latent" broad-spectrum anti-tumor drug that is effective against both leukemia and solid tumors.
Cyclophosphamide has no activity in vitro and plays an important role mainly through the hydrolysis of liver P450 enzyme to aldophosphamide, which is then transferred to tissues to form phosphoramide nitrogen mustard.Cyclophosphamide can be deactivated by dehydrogenase conversion to carboxyphosphamide or excreted as acrolein, resulting in urinary tract toxicity.It is a periodic nonspecific drug with the same mechanism of action as nitrogen mustard.
| Name | CAS | molecular | density |
| Cyclophosphamide | 50-18-0 | C7H15Cl2N2O2P | 1.093 |
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