| Customization: | Available |
|---|---|
| Grade: | Perfume Grade C |
| Function: | Respiratory System |
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| product name | DL Mevalonolactone | cas | 674-26-0 |
Description:
DL-Mevalonolactone is the δ-lactone form of mevalonic acid, a precursor in the mevalonate pathway. It induces depolarization and swelling, decreases NADPH content and aconitase (ACO) activity, and increases malondialdehyde (MDA) production in calcium-loaded rat brain mitochondria. DL-Mevalonolactone reverses decreases in glucose uptake induced by simvastatin (Item Nos. 10010344 | 10010345) in L6 myotubes. Tissue levels and urinary excretion of DL-mevalonolactone are increased in patients with mevalonic aciduria, a disorder characterized by a deficiency in mevalonic kinase activity.
| Analytical Items | Standard | ||
| Appearance | White crystalline powder | ||
| Identification | Similar with the Reference Spectrum | ||
| Optical Rotation | -15.5°~ -17.5° | ||
| Clearity & color of solution | Clear & Colorless | ||
| Heavy Metals | ≤10ppm | ||
| Pb | ≤3ppm | ||
| As | ≤1ppm | ||
| Cd | ≤1ppm | ||
| Hg | ≤0.1ppm | ||
| Related substances | Total | ≤2.0% | |
| GSSG | ≤1.5% | ||
| Loss on drying | ≤0.5% | ||
| Residue on ignition | ≤0.1% | ||
| Assay | 98.0% - 101.0% | ||
| Microbiology | |||
| Total plate count | ≤1000cfu/g | ||
| Yeast and mold count | ≤100cfu/g | ||
| Total coli forms | ≤100cfu/g | ||
| E. coli | Negative/10g | ||
| S. aureus | Negative/10g | ||
| Salmonella | Negative/10g | ||
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