cas 64461-82-1 Safe shipment Tizanidina Tizanidin hcl powder Tizanidine Hydrochloride
| Product name |
Tizanidine hydrochloride |
| CAS No. |
64461-82-1 |
| Molecular formula |
C9H9Cl2N5S |
| Molecular weight |
290.17 |
| EINECS number |
|
| Melting point |
280 °C |
| Storage condition |
Room Temperature |
| Purity |
>99% |
| Standard |
Pharmaceutical Grade |
| Appearance |
White or almost white crystal powder |
Tizanidine hydrochloride (Zanaflex) is a drug that is used as a muscle relaxant. It is a centrally acting α-2 adrenergic agonist. It is used to treat the spasms, cramping, and tightness of muscles caused by medical problems such as multiple sclerosis, spastic diplegia.
Besides, as a sleep aid and an anticonvulsant, tizanidine hydrochloride has off-label usage for migraine headaches and is effective for some symptoms of fibromyalgia.
Tizanidine as an adrenergic agonist with muscle relaxant activity, tizanidine hydrochloride belongs to the hydrochloride salt form of tizanidine, which is commonly used in the treatment of spasticity, a condition where muscles in human body spasm, cramp, or become tight induced by a variety of medical problems such as multiple sclerosis, spinal cord injury, Lou Gehrig's disease, spastic diplegia, back pain or certain other injuries to the spine or central nervous system. Besides, as a sleep aid and an anticonvulsant, tizanidine hydrochloride has off-label usage for migraine headaches and is effective for some symptoms of fibromyalgia.
As a short-acting muscle relaxer, the antinociceptive effect of tizanidine hydrochloride functions by blocking excess nerve impulses (pain sensations) of the nerve cells that are sent to the brain and control muscle movement, ultimately resulting in muscle relaxation and spasticity alleviation.
Function:
Tizanidine is a central muscle relaxant that selectively inhibits the multi-synaptic mechanism associated with muscle over-stress, mainly reducing the release of excitatory amino acids from interneurons, does not affect neuromuscular transmission, relieves muscle spasm, and is derived from the spinal cord and The brain is chronic and straight and effective.
It is clinically used for tendon pain, postoperative pain, neck and lumbar syndrome, disc herniation and spinal cord injury, multiple sclerosis, cerebrovascular accident and cerebral palsy.
Application
Tizanidine is used to help relax certain muscles in yout body. It relieves spasms, cramping, and tightness of the muscles caused by medical problems, such as multiple sclerosis or certain injuries to the spine.
| Item |
Specification |
| Appearance |
White or almost white crystalline powder |
| Indentification by (IR) |
positive |
| Melting point |
107-109 °C |
| Loss on drying |
0.5%max |
| Heavy metal |
15PPMmax |
| Residue |
0.1%max |
| Assay(by HPLC) |
97.0-103.0% |
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