Cas:1403-66-3 Gentamicin powder
product name |
Amikacin powder |
cas number |
1403-66-3 |
apperance |
white powder |
Density |
1.3±0.1 g/cm3 |
MF |
C60H123N15O21 |
MW |
477.595 |
Gentamicin is one of the few thermostable antibiotics, so it is widely used in media preparation. The broad-spectrum antibiotics independently developed by China are one of the great scientific and technological achievements since the founding of New China. It was first developed in 1967 and was successfully identified at the end of 1969. It was named "Gentamicin", which means celebrating the "Ninth Congress" and celebrating the greatness of the working class. Gentamicin [Gentamicin, gentamycin (gentamycin)] is extracted from the fermentation broth of Monospores of the Actinomycete family. It is a basic compound and is a commonly used aminoglycoside antibiotic. Mainly used to treat bacterial infections, especially infections caused by Gram-negative bacteria. Gentamicin can bind to the 30s subunit of the bacterial ribosome and block bacterial protein synthesis.
1. It is suitable for the treatment of neonatal sepsis and sepsis caused by sensitive bacteria.
2. It is suitable for the treatment of respiratory tract infections, peritonitis and biliary tract infections caused by sensitive bacteria.
3. It is suitable for the treatment of genitourinary system infections caused by sensitive bacteria (except for initial treatment of simple urinary tract infections).
4. It is suitable for the treatment of skin and soft tissue infections and burn infections caused by sensitive bacteria.
5. Oral can be used to prepare for intestinal infection or colon surgery
6. Intramuscular injection combined with clindamycin or metronidazole can be used to reduce the incidence of infection after colon surgery.
7. Intrathecal injection can be used as an adjuvant treatment for severe central nervous system infections (acute purulent meningitis, ventriculitis) caused by Pseudomonas aeruginosa or Staphylococcus.
8. Gentamicin can also be used to treat listeriosis.
9. Gentamicin eye drops are suitable for conjunctivitis, keratitis and tears caused by coagulase-negative and positive Staphylococcus, Pseudomonas aeruginosa, Escherichia coli, Pneumoniae bacillus and other Gram-negative bacilli and Neisseria gonorrhoeae. Bunchitis, blepharitis, meibomitis, etc.