Customization: | Available |
---|---|
Powder: | Yes |
Customized: | Customized |
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Product Name: Cefotaxime sodium
CAS NO: 64485-93-4
Purity: 99%min
Appearance: This product is white, almost white or yellowish white crystalline powder; odorless or slight special smell. It is free soluble in water, slightly soluble in ethanol.
Application:
Treatment of infections of lower respiratory tract including pneumonia, urinary tract, skin and skin structures, bone and joints; treatment of bacteremia/septicemia, CNS infections, intra-abdominal infections including peritonitis, gynecological infections including pelvic inflammatory disease, endometritis and pelvic cellulitis caused by susceptible strains of specific microorganisms; perioperative prophylaxis.
It is not as effective against cefazolin as Gram-positive bacteria. Enterococci are resistant to this product. It is not effective against -resistant pneumococcus. It has strong bactericidal activity against Gram-negative bacteria. It is effective against E. coli, influenza, bacillus, and singularities. Proteus and Salmonella have stronger effects than cefoperazone, weak or resistant to Bacteroides fragilis, and Pseudomonas aeruginosa and Enterobacter cloacae are not sensitive to this product.
ITEMS |
SPECIFICATION |
RESULTS |
Appearance |
White to pale yellow Crystalline Powder |
Passed |
Identification |
IR Spectrum HPLC RT Sodium |
Passed Passed Passed |
Clarity |
Clear |
Passed |
Color of Solution |
NMT 0.2(430mm,10% solution) |
Passed |
Specific optical rotation |
+56°~+64° |
+61° |
PH |
4.5~6.5 |
5.5 |
Loss on drying |
≤3.0% |
2.7% |
Chromatographic purity Individual impurity Total impurity |
≤1.0% ≤3.0% |
≤0.6% ≤2.0% |
Sterility |
Sterile |
Passed |
Bacterial Endotoxins |
NMT 0.20 USP EU/mg |
Passed |
Particulate matter |
≥10um NMT 6000 ≥25 um NMT 600 |
Passed Passed |
Assay(HPLC) |
916-964μg/mg |
940μg/mg |
Storage Condition |
Preserve in tight container. |