Cas:64221-86-9 Imipenem powder
| product name |
Aztreonam |
| cas number |
78110-38-0 |
| apperance |
white powder |
| Density |
1.83 |
| MF |
C13H17N5O8S2 |
| MW |
435.433 |
Physical and chemical properties
Appearance and properties: white to off-white crystals
Density: 1.83g/cm3
Melting point: 227°C
Refractive index: 1.74
Storage conditions: ventilated, low temperature and dry
Security Information
Customs code: 2942000000
WGK Germany: 2
Hazard category code: R20/21/22; R36/37/38
Safety instructions: S22-S24/25
RTECS number: UA2451400
Dangerous goods mark: Xn
Physical data
1. Characters: white to off-white crystals
2. Density (g/mL, 25/4ºC): 1.83
3. Melting point (ºC): 227
4. Refractive index: 1.74
5. Solubility: soluble in dimethylformamide, slightly soluble in methanol, very slightly soluble in ethanol, almost insoluble in toluene, chloroform or ethyl acetate.
Toxicological data
1. Acute toxicity: rat (oral) LD50: >10mg/kg
Rat (peritoneum) LD50: 2,549 mg/kg
Rat (subcutaneous) LD50: 3,154 mg/kg
Rat (venous) LD50: 2,001 mg/kg
Mouse (oral) LD50: >10mg/kg
Mouse (peritoneum) LD50: 2,897mg/kg
Mouse (subcutaneous) LD50: 3,906mg/kg
Mouse (intravenous) LD50: 1,963mg/kg
Since the LD50 of table salt is 3,000 mg/kg, the acute toxicity of BPA is the same as that of table salt.
Ecological data
Usually it is not harmful to water. If there is no government permission, do not discharge the material into the surrounding environment.
1. Urinary tract infections: simple and complex pyelonephritis caused by Escherichia coli, Proteus mirabilis, Pseudomonas aeruginosa, Enterobacter cloacae, Klebsiella odorifera, Citrobacter, Serratia marcescens And recurrent cystitis. 2. Lower respiratory tract infections: Pneumonia and bronchitis caused by Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, Haemophilus influenzae, Proteus mirabilis, Enterobacter and Serratia marcescens.
3. Bloodstream infections: bloodstream infections caused by Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, Proteus mirabilis, Serratia marcescens and Enterobacter.
4. Skin and soft tissue infections: skin and soft tissue infections (including surgical wound infections) caused by Escherichia coli, Proteus mirabilis, Serratia marcescens, Enterobacter, Pseudomonas aeruginosa, Klebsiella pneumoniae, and Citrobacter , Ulcer and burn wound infection).
5. Peritonitis and other abdominal infections: including Escherichia coli, Klebsiella smelly nose, Klebsiella pneumoniae, Enterobacter cloacae, Pseudomonas aeruginosa, Citrobacter, and Serratia marcescens. Often need to be combined with anti-anaerobic drugs such as metronidazole.
6. Reproductive tract infections: Gynecological infections such as Escherichia coli, Klebsiella pneumoniae, Enterobacter (including Enterobacter cloacae), Pseudomonas aeruginosa, Proteus mirabilis, such as endometritis, pelvic inflammatory disease, etc. It needs to be combined with anti-anaerobic drugs such as metronidazole.
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