CAS: 1404-04-2 Neomycin

• Varieties: Growth Promoting Medicine
• Component: Botany
• Type: The First Class
• Pharmacodynamic Influential Factors: Animal Species
• Storage Method: Cool Dry Place
• CAS: 1404-04-2
• Model NO.: Neomycin
• Mf: C23h52n6o25s3
• MW: 614.644
• Usage: Animal Pharmaceuticals
• Appearance: White Powder
• Shelf Life: 24 Months
• Transport Package: 1kg/Bag, 25kg/Drum
• Specification: 99%
• Trademark: HNB
• Origin: China
• HS Code: 3006920000
• Production Capacity: 5000kg/Month

Product Description

Produciton name	Neomycin
CAS	1404-04-2
Apperance	White powder
Density	1.6±0.1 g/cm3
MF	C23H52N6O25S3
MW	614.644

Neomycin is An antibiotic, which belongs to the aminoglycoside antibiotic together with streptomycin, kanamycin, and gentamicin. It is produced by Streptomyces freundii; it is effective against both Gram-positive and Gram-negative bacteria. The product is mainly a mixture of neomycin B and C. Neomycin has complete cross-resistance with kanamycin, and partial cross-resistance with streptomycin; similar to similar antibiotics, it has nephrotoxicity and inner ear toxicity, and its damage to the inner ear is often irreversible.

Function
Preparation before colon surgery, as adjuvant treatment when hepatic coma. Neomycin is not suitable for the treatment of systemic infections. This product is not effective against Pseudomonas aeruginosa. Neomycin has a strong antibacterial effect on Mycobacterium tuberculosis, and its minimum inhibitory concentration is generally 0.5mg/ml. Most non-tuberculous mycobacteria are resistant to this product. Neomycin is also effective against many gram-negative bacilli such as Escherichia coli, Klebsiella, Proteus, Enterobacter, Salmonella, Shigella, Brucella, Pasteurella, etc. It has antibacterial effect; Neisseria meningitidis and Neisseria gonorrhoeae are also sensitive to this product. Neomycin has a poor effect on Staphylococcus and other gram-positive cocci. Each group of streptococci, Pseudomonas aeruginosa and anaerobic bacteria are resistant to this product. Neomycin mainly binds to the 30S subunit of bacterial ribosomes and inhibits bacterial protein synthesis. Bacteria can easily develop resistance after contact with neomycin. The combined application of neomycin and other antibacterial drugs or anti-tuberculosis drugs can reduce or delay the development of drug resistance. The product is white or almost white powder.