Cas:93106-60-6 Enrofloxacin powder
| product name |
Enrofloxacin |
| cas number |
93106-60-6 |
| apperance |
white powder |
| Density |
1.4±0.1 g/cm3 |
| MF |
C19H22FN3O3 |
| MW |
359.395 |
Enrofloxacin is also known as ethyl ciprofloxacin and enrofloxacin. It is a yellowish or light yellow crystalline powder with bitter taste and insoluble in water. This product is designated as a special animal medicine by the state.
System name: 1-cyclopropyl-7-(4-ethyl-1-piperazinyl)-6-fluoro-1,4-dihydro-4-oxo-3-quinoline carboxylic acid.
Enrofloxacin belongs to the chemically synthesized bacteriostatic agent of Fluoroquinolones and is easily soluble in organic solvents such as sodium hydroxide solution, methanol and methyl cyanide.
The absorption of oral and intramuscular injection is rapid and complete, and the blood drug level reaches its peak within 0.5-2 hours. Except for the central nervous system, almost all tissues have higher drug concentrations than plasma, which is beneficial to the treatment of systemic infections and deep tissue infections. This product is eliminated by renal and non-renal means, and about 15%-50% of the original form of the drug is excreted through urine. The metabolism in animals is mainly to remove the ethyl group and become ciprofloxacin.
This product is a broad-spectrum bactericide with specific effects on mycoplasma. It has bactericidal effect on Escherichia coli, Klebsiella, Salmonella, Proteus, Pseudomonas aeruginosa, Haemophilus, Pasteurella multocida, Pasteurella hemolyticus, Staphylococcus aureus, Streptococcus, etc.
Enrofloxacin can be used as an animal drug. It has a long half-life in the animal body and has good tissue distribution. It is a broad-acting bacteriostatic agent. It has bacteriostatic effect on Gram-positive bacteria, negative bacteria and mycoplasma. It is used for the control of vibrio and colibacillosis in farmed fish.
This product is a synthetic third-generation quinolone antibacterial drug, also known as ethyl ciprofloxacin. It was approved by the FDA on October 4, 1996. It is a special quinolone antibacterial drug for livestock, poultry and aquatic products. It can bind to bacterial DNA gyrase subunit A, thereby inhibiting the enzyme's cutting and joining functions, preventing bacterial DNA replication, and exhibiting antibacterial effects. It has broad-spectrum antibacterial activity and strong permeability. This product has a strong killing effect on gram-negative bacteria and good antibacterial effect on gram-positive bacteria. It has good oral absorption and high blood concentration. It is stable and can be widely distributed in tissues. Its metabolite is ciprofloxacin, which still has a strong antibacterial effect. It has strong antibacterial activity against almost all pathogenic bacteria in aquatic animals. It is effective against severe infections caused by drug-resistant pathogens, and has no cross-resistance to other antibiotics
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