| Customization: | Available |
|---|---|
| Powder: | Yes |
| Customized: | Customized |
|
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| Product name | Diprophylline |
| Appearance | White powder |
| CAS No. | 479-18-5 |
| MF | C10H14N4O4 |
| MW | 254.24 |
| Assay | 99%min |
| EINECS | 207-526-1 |
It is an inhibitor to phosphodiesterase.
It is used in the therapy of bronchial asthma, gasping bronchitis and gasping from cardiogenic pulmonary edema.
It can soothe the symptom of gasping through loosening bronchial smooth muscle, increasing cardiac blood output, expanding kidney arteriole, increasing glomerulus filtration and renal blood flow, inhibiting distal end renal tubule's reabsorption of sodion and chloridion, and increasing contractility of hanging skeletal muscle.
Its action of expanding bronchus is only one tenth of that of aminophylline.
It can easily be absorbed orally, metabolize to derivants of theophylline in vivo, and are excreted with urine.
|
Item |
Specification |
|
Specific rotation |
+39.5 to +41.5° |
|
State of solution(transmittance) |
Clear 98.0% min. |
|
Chloride[cl] |
0.020% max. |
|
Ammonium [NH4] |
0.02% max. |
|
Sulfate[SO4] |
0.020% max |
|
Iron[Fe] |
10ppm max. |
|
Heavy metals [Pb] |
10ppm max |
|
Arsenic[As2O3] |
1ppm max |
|
Other amino acids |
Chromatographically not detectable |
|
Loss on drying |
0.20% max. |
|
Residue on ignition[sulfated] |
0.10% max. |
|
Assay |
99.0% min |
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