| Customization: | Available |
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| Powder: | Yes |
| Customized: | Customized |
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Chlortetracycline, the chemical name is chlorotetracycline, the chemical formula is C22H23ClN2O8, is a golden yellow crystalline powder, produced by fermentation of Streptomyces aureus, the fermentation broth is acidified and filtered to obtain a precipitate, which is dissolved in ethanol and then precipitated by acid. The crude product is dissolved and formed into a salt to obtain hydrochloride crystals.
Chlortetracycline is a tetracycline antibiotic, and many rickettsia, mycoplasma, chlamydia, atypical mycobacteria and spirochetes are sensitive to chlortetracycline. Enterococcus is resistant to it. Over the years, due to the wide application of tetracyclines, common clinical pathogens are seriously resistant to chlortetracycline, and gram-positive bacteria such as Staphylococcus and most Enterobacteriaceae are resistant. Cross-resistance exists between different varieties of chlortetracycline and tetracycline. The mechanism of action of chlortetracycline is that the drug can specifically bind to the A position of the 30S subunit of the bacterial ribosome, inhibit the growth of the peptide chain and affect the synthesis of bacterial proteins.
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Foreign name Chlorotetracycline alias chlorotetracycline Chemical formula C22H23ClN2O8 Molecular weight 478.88 CAS accession number 57-62-5 EINECS accession number 200-341-7 Melting point 168.5 ºC Boiling point 821.1 ºC water soluble very slightly soluble Density 1.7 g/cm³ Appearance golden yellow crystalline powder Flash point 450.4 ºC Apply antibiotics |
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