Sparfloxacin Powder CAS 110871-86-8

• Powder: Yes
• Customized: Customized
• Certification: ISO 9001, USP, BP
• State: Powder
• Purity: >99%
• CAS: 110871-86-8
• Model NO.: Sparfloxacin
• Mf: C19h22f2n4o3
• MW: 359.3947
• Color: White
• Melting Point: 265c
• Boiling Point: 575.9c at 760 Mmhg
• Density: 1.347g/cm3
• Shelf Life: 24month
• Storage: Cool Dry Place
• Transport Package: 1kg/Bag, 25kg/Drum
• Specification: Sparfloxacin
• Trademark: HNB
• Origin: China
• Production Capacity: 2000kg/Month

Product Description

Sparfloxacin is a fluoroquinolone antibiotic used in the treatment of bacterial infections. Sparfloxacin exerts its antibacterial activity by inhibiting DNA gyrase, a bacterial topoisomerase. DNA gyrase is an essential enzyme which controls DNA topology and assists in DNA replication, repair, deactivation, and transcription.
 

Mechanism of Action:

Sparfloxacin is a synthetic fluoroquinolone broad-spectrum antimicrobial agent in the same class as ofloxacin and norfloxacin. Sparfloxacin has in vitro activity against a wide range of gram-negative and gram-positive microorganisms. Sparfloxacin exerts its antibacterial activity by inhibiting DNA gyrase, a bacterial topoisomerase. DNA gyrase is an essential enzyme which controls DNA topology and assists in DNA replication, repair, deactivation, and transcription. Quinolones differ in chemical structure and mode of action from (beta)-lactam antibiotics. Quinolones may, therefore, be active against bacteria resistant to (beta)-lactam antibiotics. Although cross-resistance has been observed between sparfloxacin and other fluoroquinolones, some microorganisms resistant to other fluoroquinolones may be susceptible to sparfloxacin. 
 

Productname	Sparfloxacin
CAS NO.	110871-86-8
MW	359.3947
MF	C19H22FN3O3
Category	Pharmaceutical Raw Materials, Fine Chemicals, Bulk drug
Standard	Medical standard
Appearance	White to light yellow
Assay	98%
Storage	should be stored in a well-closed container at low temperature, keep away from moisture, heat and light.

Item	Standard
Structural data confirmation	1. H-NMR: The data of structure are identical with reference standard
	2. HPLC-MS: Ensure the molecular weight of main peak and fragment peak are identical with reference standard
	3. IR:The data of IR are identical with that of reference standard
Purity(HPLC)	≥99.0%
Related impurities	Specific single impurity	Meets EP/USP/BP standards
	Non-specific single impurity	≤0.10%
	Total Impurities	≤0.50%
Crystal form	Meets EP/USP/BP standards
Loss on drying	≤1.0%
Water	≤1.0%
Inorganic salt	≤0.1%
Heavy metals	≤10 ppm
Assay	99.0%~101.0%(According to EP/USP/BP standards)
Microbiological Analysis
Total plate count	≤1000cfu/g
Yeast and Moulds	≤100cfu/g
E. Coli.	Absent
Salmonella	Absent
S.aureus	Absent