Biliary medicine CAS 128-13-2 Deoxyursocholic acid/UDCA/Ursodiol powder
| Product name |
Ursodiol |
| Cas No. |
128-13-2 |
| Molecular Formula |
C24H40O4 |
| Appearance |
White powder |
Ursodiol reduces cholesterol absorption and is used to dissolve gallstones.Target: OthersUrsodiol, also known as ursodeoxycholic acid and the abbreviation UDCA, is one of the secondary bile acids, which are metabolic byproducts of intestinal bacteria. The drug reduces cholesterol absorption and is used to dissolve (cholesterol) gallstones in patients who want an alternative to surgery. The drug is very expensive, however, and if the patient stops taking it, the gallstones tend to recur if the condition that gave rise to their formation does not change. For these reasons, it has not supplanted surgical treatment by cholecystectomy.Ursodeoxycholic acid is currently the only established drug for the treatment of chronic cholestatic liver diseases. It has cytoprotective, anti-apoptotic, membrane stabilizing, anti-oxidative and immunomodulatory effects. Prolonged administration of ursodeoxycholic acid in patients with primary biliary cirrhosis (PBC) is associated with survival benefit and a delaying of liver transplantation.
Application & Function of Ursodiol
1. It is suitable for non-calcified calculi with normal gallbladder function, light transmittance and diameter of 10 ~ 15mm.
2. Prevention of gallstone formation: Ursodeoxycholic acid can be taken to prevent gallstone formation in patients who need long-term use of drugs (such as estrogen, clobebutyl ester and its derivatives, and choleenamide) that are prone to cholesterol stone formation, in those who eat a diet with high cholesterol for a long time, or in those with genetic susceptibility factors.
3. Treatment of cholecystitis, cholangitis, biliary dyspepsia, jaundice, etc.
4. For the treatment of fat diarrhea, hypertriacylglyceremia, hepatomegaly, chronic hepatitis after ilectomy, and also for bile reflux gastritis.
5. Also used for primary biliary cirrhosis and primary sclerosing cholangitis.
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