CAS 83881-52-1 Cetirizine Hydrochloride Cetirizine HCl

• Powder: Yes
• Customized: Customized
• State: Solid
• Purity: >96%
• Name: Cetirizine HCl
• CAS: 83881-52-1
• Model NO.: cetirizine
• Mf: C21h26cl2n2o3
• Transport Package: Drum
• Specification: 99%
• Trademark: HS
• Origin: China
• HS Code: 2904201000
• Production Capacity: 100000

Product Description

1.Product Name:Cetirizine Hydrochloride
2.Purity:99%
3.Molecular Weight:461.81
4.Test method:HPLC
5.Appearance:White Powder
6.Melting point:110-115°C
7.Water Solubility:Soluble in water, DMSO, ethanol, and methanol.
8.Introduction:
Cetirizine hydrochloride is an orally-active and selective histamine (H1)-receptor antagonist. It is a second-generation antihistamine and a human metabolite of hydroxyzine. Three important features of cetirizine are: a high specificity fort he H1-receptor; a low need for metabolism, and the existence of non-H1-dependent activities on cells involved in the pathogenesis of allergy.
 

Cetirizine is a second generation antihistamine used in the treatment of hay fever, allergies, angioedema, and urticaria.It is a major metabolite of hydroxyzine, and a racemicselective H1 receptor antagonist.

1. Cetirizine is mainly used for urticaria and skin itch caused by allergy ;
2. Cetirizine is used to treat tardive and pressure urticaria,can replace glucocorticoid to be as regular treatment but should be used a large amount;
3. Cetirizine can also have the function for cold urticaria. 

TEST	SPECIFICATION	RESULT
Appreance	White or almost white powder	almost white powder
Identification	Postitive	confirms
pH	1.2-1.8	1.54
Loss on drying	≤0.5%	0.15%
Residue on Ignition	≤0.2%	0.03%
Clolor of Solution	≤BY7	confirms
Heavy metals	≤10ppm	confirms
Single Impurity	≤0.1%	0.10%
Total Impurity	≤0.3%	0.28%
Assay	99%-100.5%	99.78%
Aceton	≤0.5%	0.01%