CAS 51-05-8 High Purity Procaine HCl

• Powder: Yes
• Customized: Customized
• Certification: GMP, ISO 9001, USP
• Suitable for: Elderly
• State: White Crystalline Powder
• Purity: 99%
• Model NO.: Procaine HCl
• Mf: C13h21cln2o2
• Shelf Life: 24 Months
• Storage: Cool Dry Place
• Einecs: 200-077-2
• Transport Package: 1kg/Bag, 25kg/Drum
• Specification: Procaine HCl
• Trademark: HNB
• Origin: China
• HS Code: 2922499990
• Production Capacity: 2000kg/Month

Product Description

Product Name	Procaine Hydrochloride
CAS NO:	51-05-8
Molecular Formular	C13H21ClN2O2
EINECS NO	200-077-2
Purity	99-101%
Appearance	White crystalline powder

Procaine HCl is a local anesthetic drug of the amino ester group. It is used primarily to reduce the pain of intramuscular injection of penicillin, and it is also used in dentistry. It acts mainly by being a sodium channel blocker. Today it is used therapeutically in some countries due to its sympatholytic, anti-inflammatory, perfusion enhancing, and mood enhancing effects.

Procaine HCl Application:

Procaine HCl is a local anesthetic drug of the amino ester group. It is used primarily to reduce the pain of intramuscular injection of penicillin, and it is also used in dentistry. Owing to the ubiquity of the trade name Novocain. It acts mainly by being a sodium channel blocker.Today it is used therapeutically in some countries due to its sympatholytic, anti-inflammatory, perfusion enhancing, and mood enhancing effects.
Procaine HCl is indicated for the production of local or regional analgesia and anesthesia by local infiltration and peripheral nerve block techniques.
 
Application of procaine leads to the depression of neuronal activity. The depression causes the nervous system to become hypersensitive producing restlessness and shaking, leading to minor to severe convulsions. Studies on animals have shown the use of procaine led to the increase of dopamine and serotonin levels in the brain.Other issues may occur because of varying individual tolerance to procaine dosage. Nervousness and dizziness can arise from the excitation of the central nervous system, which may lead to respiratory failure if overdosed. Procaine may also induce weakening of the myocardium leading to cardiac arrest.
 
Procaine can also cause allergic reactions causing the individuals to have problems with breathing, rashes, and swelling. Allergic reactions to procaine are usually not in response to procaine itself, but to its metabolite PABA. About one in 3000 people have an atypical form of pseudocholinesterase,[citation needed] which does not hydrolyze ester anesthetics such as procaine, resulting in a prolonged period of high levels of the anesthetic in the blood and increased toxicity.

Test Items	Specification	Test Results
Appearance	White crystals or a white crystalline powder	Conform
Identification	A\B\E. It appears positive reaction
Melting point	154degree~158degree	154degree~157degree
Acidity	PH 5.0~6.5	PH=5.9
Appearance of solution	Clear and colourless	Conform
Loss on drying	≤0.5%	0.07%
Heavy metals	≤0.0005%	Conform
Related substances	≤0.05%	Conform
Sulphated ash	≤0.1%	0.05%
Assay ( on dry basis )	99.0-101.0%	99.87%
Conclusion	Conform to BP2005