Pharma Grade CAS 80-35-3 Strength Product 99% Sulfadoxine Sodium

• Varieties: Infectious Disease Prevention Medicine
• Component: Animal
• Type: The First Class
• Pharmacodynamic Influential Factors: Animal Species
• Storage Method: Prevent High or LowTemperature
• Veterinary Reg. No.: Pyu98665
• Model NO.: sulfadoxine
• Name: Sulfadoxine
• CAS: 2447-57-6
• Mf: C12h14n4o4s
• Transport Package: Drum
• Specification: 99%
• Trademark: HS
• Origin: China
• HS Code: 2904201000
• Production Capacity: 100000

Product Description

 

Product Name	Sulfadoxine
CAS NO	2447-57-6
Application	Pharmaceutical intermediates
Appearance	White crystalline Powder
Transportation	Sea,Air
Molecular Weight	310.33
Molecular Formula	C12H14N4O4S
Melting Point	190-194°C
Boiling Point	298°C (rough estimate)
Density	1.4006 (rough estimate)
Storage	2-8°C

What's Sulfadoxine? 

Isoniazid is an antibacterial agent used primarily as a tuberculostatic. Target: Antibacterial Isoniazid is a prodrug and must be activated by a bacterial catalase-peroxidase enzyme that in M. tuberculosis is called KatG. KatG couples the isonicotinic acyl with NADH to form isonicotinic acyl-NADH complex. This complex binds tightly to the enoyl-acyl carrier protein reductase known as InhA, thereby blocking the natural enoyl-AcpM substrate and the action of fatty acid synthase. This process inhibits the synthesis of mycolic acid, required for the mycobacterial cell wall. A range of radicals are produced by KatG activation of isoniazid, including nitric oxide, which has also been shown to be important in the action of another antimycobacterial prodrug PA-824. Isoniazid is bactericidal to rapidly dividing mycobacteria, but is bacteriostatic if the mycobacteria are slow-growing.

 

Application & Function of Sulfadoxine

1.Antituberculosis inhibits and kills Mycobacterium tuberculosis. Its biomembrane permeability is good. Because of its good curative effect, low toxicity, low cost, and convenience for oral administration, it is listed as the first choice antituberculosis drug.

2.Antidepressant Isoniazid is also the first antidepressant drug, but it exits the market because of its hepatotoxicity.

3.Antibacterial Isoniazid is highly selective for Mycobacterium tuberculosis, strong antibacterial activity, bacteria have bactericidal effect.