CAS 80-08-0 High Quality 99% 4, 4′ -Diaminodiphenylsulfone (DDS/Dapsone)

• Powder: Yes
• Customized: Customized
• Certification: GMP, ISO 9001, USP, BP
• State: White Crystalline Powder
• Purity: >99%
• CAS: 80-08-0
• Model NO.: 4, 4′-Diaminodiphenylsulfone
• Mf: C12h12n2o2s
• Merck: 14, 2822
• Density: 1.2701 (Rough Estimate)
• Einecs No.: 201-248-4
• Shelf Life: 24 Months
• Storga: Cool Dry Place
• Transport Package: 1kg/Bag, 24kg/Drum
• Specification: 4, 4′-Diaminodiphenylsulfone
• Trademark: HNB
• Origin: China
• Production Capacity: 2000kg/Month

Product Description

Product Name	4,4'-Diaminodiphenylsulfone
CAS No.	80-08-0
EINECS	201-248-4
Molecular Formula	C12H12N2O2S
Molecular Weight	248.3
Appearance	White Crystalline Powder

Functions:

Dapsone (4,4 -sulfonylbisbenzeneamine; 4,4 -sulfonyldianiline;p,p -diaminodiphenylsulfone; 

or DDS [Avlosulfon])occurs as an odorless, white crystalline powder that is veryslightly soluble 

in water and sparingly soluble in alcohol.The pure compound is light stable, but traces of impurities,including water, make it photosensitive and thus susceptibleto discoloration in light.
Although no chemical change is detectablefollowing discoloration, the drug should be protectedfrom 

light. Dapsone is used in the treatment of both lepromatous andtuberculoid types of leprosy. 

Dapsone is used widely for allforms of leprosy, often in combination with clofazimine andrifampin. 

Initial treatment often includes rifampin with dapsone,followed by dapsone alone. It is also used to preventthe occurrence of multibacillary leprosy when given prophylactically.
Serious side effects can include hemolytic anemia,methemoglobinemia, and toxic hepatic effects. Hemolyticeffects can be pronounced in patients with glucose-6-phosphatedehydrogenase deficiency. During therapy, all patientsrequire frequent blood counts.
Dapsone is approved for the treatment of an autoimmune blistering skin disease, dermatitis herpetiformis. This intensely pruritic eruption is characterized histologically by a dense dermal infiltration of neutrophils and subepidermal blisters. Other skin diseases in which dapsone is helpful are linear immunoglobulin A (IgA) dermatosis, subcorneal pustular dermatosis, leukocytoclastic vasculitis, and a variety of rarer eruptions in which neutrophils predominate, including some forms of cutaneous lupus erythematosus.

 

Applications :

1. for polysulfone amide and other polymers

2. as epoxy hardener
3. as adhesives
4. as gas chromatography
5. for anti-leprosy drug
The above usages mainly involve in aerospace industry, laminates industry, insulated materials, 

weaving machines and pharmaceutical

 

ITEM	INDEX
Appearance	White powder
Identification	IR
Heavy metal	≤10ppm
Pb	≤3ppm
Hg	≤0.1ppm
Cd	≤1ppm
Loss on drying	≤0.5%
Residue on lgnition	≤0.1%
Single impurity	≤0.5%
Total impurity	≤1.0%
Total bacteria	≤1000cfu/g
Yeast and Mould	≤100 cfu/g
E.coli/25g	Absent
Salmonella/25g	Absent
Assay	≥99.0%
Conclusion	Conforms with USP/EP standards