Cas:1404-90-6 Vancomycin powder
| product name |
Thiamphenicol |
| cas number |
1404-90-6 |
| apperance |
white powder |
| Density |
1.65 g/cm3 |
| MF |
C66H75Cl2N9O24 |
| MW |
1449.25 |
English name: Vancomycin
CAS Number: 1404-90-6
Molecular formula: C66H75Cl2N9O24
Molecular weight: 1449.25
PSA: 530.49000
LogP: 4.73460
Physical and chemical properties
Appearance and properties: almost white powder
Density: 1.65 g/cm3
This product has a good antibacterial effect on most gram-positive bacteria including Staphylococcus aureus and coagulase-negative Staphylococcus methicillin-sensitive and resistant strains, various streptococci, Streptococcus pneumoniae and Enterococcus.
1. Kill bacteria by inhibiting the growth and reproduction of bacteria. This drug interferes with the synthesis of the cell wall by interfering with peptidoglycan, a key component in the structure of the bacterial cell wall, and inhibits the production of phospholipids and polypeptides in the cell wall.
2. Vancomycin is mainly used in the treatment of infections in four aspects: first, the treatment of drug-resistant bacterial infections; in addition, it is also used in the treatment of antibiotic-resistant pseudomembranous enteritis caused by Clostridium difficile.
3. Vancomycin can also be used to treat colitis and intestinal inflammation; Vancomycin is also often used to prevent infection when installing cardiac catheters, venous catheters and other devices. Vancomycin can be used alone or in combination.
4. It can inhibit the synthesis of bacterial cell walls, has a strong effect on Staphylococcus aureus, Streptococcus pyogenes, Streptococcus pneumoniae, etc., and has a good effect on Bacillus difficile, Bacillus anthracis, and Bacillus diphtheria.
5. There is no cross-resistance to other antibiotics, and there are very few resistant strains. Mainly used for endocarditis, sepsis, pseudomembranous enteritis, etc.
6. The medicine is not absorbed by oral administration. It must be dissolved with water for injection before intravenous infusion, and the instillation time should not be less than 1 hour. Too fast intravenous infusion can cause skin reactions, and too high concentration can cause thrombophlebitis; intramuscular injection can cause severe pain, so intramuscular injection is not allowed; it has severe ototoxicity and nephrotoxicity, so it should only be used for short-term rescue.
This product is limited to systemic infections caused by methicillin-resistant Staphylococcus aureus (MRSA) and intestinal infections and systemic infections caused by Clostridium difficile; penicillin or cephalosporins should not be used for penicillin allergics For patients with severe staphylococcal infection who have failed to treat with the above antibiotics, norvancomycin can be used. This product is also used for the treatment of enterococcal endocarditis and corynebacterium (diphtheria-like) endocarditis in people allergic to penicillin. Treatment of arterial and venous shunt infections caused by Staphylococcus in hemodialysis patients who are allergic to penicillin and not allergic to penicillin.
Audited Supplier 
){kind=link}
){kind=link}