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Ursodeoxycholic acid CAS 128-13-2 | ||
Ursodeoxycholic acid | CAS 128-13-2 | Brand: HNB |
MF C24H40O4 | EINECS 204-879-3 | |
MW 392.57 | Min order: 10grams | |
Categories:Bile Acids;Biochemistry;Steroids;Intermediates & Fine Chemicals;Pharmaceuticals;API's;API;Herb extract | ||
Usage | Ursodeoxycholic acid, Used as an anticholelithogenic. Epimer with Chenodiol with respect to the hydroxyl group at C7. | |
Applications | Ursodeoxycholic acid ,Pharmaceutical raw materials |
1.product Name: Ursodeoxycholic Acid
2.CAS No.: 128-13-2
3. Other Names: UDCA
4. MF: C24H40O4
5..Purity: 99% min
6..Appearance:White or almost white crystal powder
Ursodeoxycholic acid is white crystal powder,almost insoluble in water,freely soluble in alcohol
Ursodeoxycholic acid (UDCA), also known as ursodiol, is a compound produced from bile by the action of intestinal bacteria. Since this bile acid is not produced directly by the body, it is known as a secondary bile acid.One of the functions of bile acids is to act in the intestine to help digest fats and fatsoluble vitamins from food. Ursodeoxycholic acid has been used in pharmacology to dissolve gallstones made of cholesterol, and to treat liver disorders. It has been used for a long time in both human and veterinary medicine.
Function:
Ursodeoxycholic acid can be chemically synthesized. Ursodeoxycholic acid reduces cholesterol absorption and is used to dissolve (cholesterol) gallstones in patients who want an alternative to surgery. The drug is very expensive, however, and if the patient stops taking it, the gallstones tend to recur if the condition that gave rise to their formation does not change. For these reasons, Ursodeoxycholic acid has not supplanted surgical treatment by cholecystectomy.
UDCA is used to treat primary biliary cirrhosis. In children, its use is not licensed, as its safety and effectiveness are not established. Ursodeoxycholic acid reduces elevated liver enzyme levels by facilitating bile flow through the liver and protecting liver cells.
Test item | Test standard | Test result |
Appearance | White or almost white crystalline powder, taste bitter, without stink | Complied |
Identification | Enterprise Standard | Complied |
Related Substance | Lithocholic Acid ≤ 0. 1% | Complied |
Specific Optical Rotation | +58° - +62° | +62° |
Melting Point | 200ºC -204ºC | 202.9ºC-203.9ºC |
Loss on Drying | ≤ 1.0% | 0.11% |
Ignition Residue | ≤ 0.1% | 0.08% |
Heavy Mental | ≤ 10ppm | Complied |
Assay (Titration) | ≥ 99.0%-101% | 100.4% |
Purity (HPLC) | CDCA ≤ 1.0% Other Max. Individual Impurity ≤ 0.1% Total Impurity ≤1.5% |
CDCA:Not detected Other Max.Individual Impurity:0.08% Total Impurity:0.21% |