| Customization: | Available |
|---|---|
| Powder: | Yes |
| Customized: | Customized |
|
Still deciding? Get samples of US$ 80/kg
Request Sample
|
Suppliers with verified business licenses
Audited Supplier Audited by an independent third-party inspection agency
|
Name |
Piperaquine phosphate |
|
Brand |
Excolla |
|
Molecular Formula |
C29H32Cl2N6.4(H3PO4).4(H2O) |
|
Molecular Weight |
999.56 |
|
CAS Registry Number |
4085-31-8 |
Piperaquine is an antimalarial drug, a bisquinoline first made in the 1960s, and used extensively in China and Indochina as prophylaxis and treatment during the next 20 years. Usage declined in the 1980s as piperaquine-resistant strains of P. falciparum arose and artemisinin-based antimalarials became available. However, Chinese scientists have been studying whether piperaquine can still be used therapeutically in combination with artemisinin.
Piperaquine is characterized by slow absorption and a long biological half-life, making it a good partner drug with artemisinin derivatives which are fast acting but have a short biological half-life.
|
Item |
Specification |
|
Specific rotation |
+39.5 to +41.5° |
|
State of solution(transmittance) |
Clear 98.0% min. |
|
Chloride[cl] |
0.020% max. |
|
Ammonium [NH4] |
0.02% max. |
|
Sulfate[SO4] |
0.020% max |
|
Iron[Fe] |
10ppm max. |
|
Heavy metals [Pb] |
10ppm max |
|
Arsenic[As2O3] |
1ppm max |
|
Other amino acids |
Chromatographically not detectable |
|
Loss on drying |
0.20% max. |
|
Residue on ignition[sulfated] |
0.10% max. |
|
Assay |
99.0% min |
){kind=link}