Cas:112811-59-3 Gatifloxacin powder
| product name |
Gatifloxacin |
| cas number |
112811-59-3 |
| apperance |
white powder |
| Density |
1.4±0.1 g/cm3 |
| MF |
C19H22FN3O4 |
| MW |
375.394 |
Gatifloxacin, a racemic compound of 8-methoxyfluoroquinolone, has a broad spectrum of activity against Gram-negative and positive microorganisms in vitro, and its R- and S-enantiomers have the same antibacterial activity. The antibacterial effect of gatifloxacin is to inhibit bacterial DNA replication, transcription and repair processes by inhibiting bacterial DNA gyrase and topoisomerase IV.
The results of in vitro tests and clinical use have shown that it has antibacterial activity against most strains of the following microorganisms:
1. Gram-positive bacteria: Staphylococcus aureus (limited to strains sensitive to methicillin), Streptococcus pneumoniae (strains sensitive to penicillin).
2. Gram-negative bacteria: Escherichia coli, influenza and Haemophilus parainfluenzae, Klebsiella pneumoniae, Moraxella catarrhalis, Neisseria gonorrhoeae, Proteus mirabilis.
3. Other microorganisms: Chlamydia pneumoniae, Legionella pneumoniae, Mycoplasma pneumoniae.
This product is mainly used for various infectious diseases caused by sensitive pathogens, including acute attack of chronic bronchitis, acute sinusitis, community-acquired pneumonia, simple urinary tract infection (cystitis) and complicated urinary tract infection, acute Pyelonephritis, gonococcal urinary tract inflammation or rectal infection in men and gonococcal cervical infection in women.
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