CAS1190307-88-0 Anti HCV Daclatasvir Ledipasvir Sofosbuvir

• Powder: Yes
• Customized: Customized
• Certification: GMP, HSE, ISO 9001, USP, BP
• Suitable for: Adult
• State: Solid
• Purity: >96%
• Model NO.: sofosbuvir
• Name: Sofosbuvir
• Mf: C22h29fn3o9p
• CAS: 1190307-88-0
• Transport Package: Drum
• Specification: 99%
• Trademark: HS
• Origin: China
• HS Code: 2904201000
• Production Capacity: 100000

Product Description

Introduction
Product Name: Sofosbuvir
Synonyms:   GS-7977;N-[[P(S),2'R]-2'-Deoxy-2'-fluoro-2'-methyl-P-phenyl-5'-uridylyl]-L-alanine 1-methylethyl ester;PSI 7977;sofosbuvir;GS-7977/sofosbuvir;sofosbuvir, PSI7977;(S)-isopropyl 2-(((S)-(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyriMidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-Methyltetrahydrofuran-2-yl)Methoxy)(phenoxy)phosphoryl)aMino)propanoate;PSI-7977 Discontinued

 Molecular Formula:  C22H29FN3O9P

Molecular Weight: 529.4525242

CAS No.: 1190307-88-0

Appearance:  white crystalline powder 

Puity: 99.0% up by HPLC

Usage:  treat for chronic hepatitis C

 sofosbuvir is first without joint interferon can be safe and effective drug for the treatment of certain types of hepatitis c.Clinical trials confirm for type 1 and 4 c, the drug combination of polyethylene glycol (peg) interferon and ribavirin overall sustained virological response (SVR) is as high as 90%;In view of the type 2 c, the drug plus ribavirin SVR is 89% - 95%;In view of the 3 c, the drug plus ribavirin SVR is 61% - 63%.

Function
sofosbuvir is a kind of hepatitis c virus (HCV) NS5B polymerase inhibitors nucleotide analogues, applicable to as united antiviral treatment composition in the treatment of chronic hepatitis c (CHC) infection.
sofosbuvir  confirmed by test can effectively treat genotype 1, 2, 3, or 4 c subjects, including within milan criteria are awaiting liver transplantation of HCC subjects and co-infection of HCV/HIV - 1 subjects.

Batch No.	HF150920	Quantity	850gs
Mfg. Date	Sep. 20, 2015	Package	As required
Rep. Date	Sep. 24, 2015	Exp. Date	Sep. 19, 2017
Items	Standards		Results
Appearance	White to off-white solid powder		Complies
Identification	By IR		Complies
	By HPLC		Complies
Solubility(1% H2O)	Colorless to faint yellow		Complies
Water Content	≤8.0%		5.8%
Related Substance	Any Unknown Individual Impurity: ≤1.50%		Complies
	Total Impurities: ≤3.00%		2.5%
Assay (HPLC basis on drying)	97.0%~101.5%		97.5%
Reference Standard	In-house Standard
Conclusion	The product complied to In-house standard.
Storage	Preserve in tight,light-resistant containers in a cool place