Cas:1264-72-8 Colistin sulfate powder
| product name |
Colistin sulfate |
| cas number |
1264-72-8 |
| apperance |
White powder |
| Density |
1.3±0.1 g/cm3 |
| MF |
C52H100N16O17S |
| MW |
401.457 |
Colistin sulfate, also known as colistin sulfate, Colistin, Polymyxin E, polymyxin E, and antifoam, etc., white or nearly white powder, odorless, bitter in taste, hygroscopic, easy to dissolve In water, it is slightly soluble in methanol, ethanol, almost insoluble in acetone, ether, etc., and the free alkali is slightly soluble in water. Stable in the range of PH3-7.5. Colistin sulfate is produced by polymyxa bacterium, has a strong antibacterial effect on gram-negative bacteria, and is used to treat intestinal diseases caused by gram-negative bacteria. It is better to combine with sulfadiazine.
It is mainly used to treat intestinal infections caused by Gram-negative bacilli (Escherichia coli, etc.), and it is also effective against Pseudomonas aeruginosa infections (septicemia, urinary tract infection, burn or trauma wound infection).
medicine interactions
(1) Sulfonamides and Rifford can enhance the antibacterial effect of this product on Escherichia coli, Enterobacter, Pneumoniae, Pseudomonas aeruginosa, etc. (2) This product can enhance the antibacterial effect of amphotericin B on coccidioides. (3) Combined use with muscle relaxants and neuromuscular blockers (such as aminoglycoside antibiotics, etc.) may cause muscle weakness and apnea.
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