Cas:60-54-8 Tetracycline powder
| product name |
Tetracycline |
| cas number |
60-54-8 |
| apperance |
white powder |
| Density |
1.6±0.1 g/cm3 |
| MF |
C22H24N2O8 |
| MW |
444.435 |
Tetracycline is an organic compound with a molecular formula of C22H24N2O8. It and its salts are yellow or light yellow crystals. They are extremely stable in a dry state. Except for chlortetracycline, the aqueous solutions of other tetracyclines are quite stable. Tetracyclines are soluble in dilute acid, dilute alkali, etc., slightly soluble in water and lower alcohols, but insoluble in ether and petroleum ether. Tetracycline antibiotics mainly include chlortetracycline, oxytetracycline, and tetracycline. Tetracycline antibiotics have a common chemical structure parent. Chlortetracycline and oxytetracycline are both derivatives of tetracycline. The former is chloretracyelin and the latter is oxyeracyein. The tetracycline family are both acid-base amphoteric compounds.
Tetracycline has a molecular formula of C22H24N2O8 and a molecular weight of 444.45. It is a broad-spectrum antibiotic. Yellow crystal, bitter taste, melting point 170~175ºC (decomposition). Slightly soluble in water, soluble in ethanol and acetone, stable in the air, but easy to absorb water, discoloration by strong sunlight.
Tetracycline hydrochloride is a broad-spectrum antibiotic. It has an inhibitory effect on most gram-positive and gram-negative bacteria. It has a bactericidal effect at high concentrations, and can inhibit rickettsia, trachoma virus, etc., and has a better effect on gram-negative bacilli. Its mechanism of action is mainly to prevent the combination of aminoacyl and ribonucleoprotein bodies, prevent the growth of peptide chains and protein synthesis, thereby inhibiting the growth of bacteria, and it also has a bactericidal effect at high concentrations.
There is cross-resistance between this product and oxytetracycline. Clinically, it is mainly used for bacillary dysentery, trachoma, pertussis, pneumonia, purulent meningitis, skin infections, otitis media, etc.
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