| Customization: | Available |
|---|---|
| Powder: | Yes |
| Customized: | Customized |
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| Product Name | Levomefolic Acid |
| Appearance | white powder |
| CAS | 31690-09-2 |
| MF | C20H25N7O6 |
| Density | 1.62 |
| Storage | Cool dry place |
| Introduction |
|
Levomefolic acid (INN) (also known as L-5-MTHF, L-methylfolate and L-5-methyltetrahydrofolate and (6S)-5-methyltetrahydrofolate, and (6S)-5-MTHF) is the primary biologically active form of folate used at the cellular level for DNA reproduction, the cysteine cycle and the regulation of homocysteine. It is also the form found in circulation and transported across membranes into tissues and across the blood-brain barrier. In the cell, L-methylfolate is used in the methylation of homocysteine to form methionine and tetrahydrofolate (THF). Levomefolic acid is a form of folate that plays an essential role in the body's methylation cycle. Methylation is the process by which methyl groups are added to DNA, RNA, and proteins, which regulates many critical metabolic pathways. |
| Function |
| 1. Treatment of Folate Deficiency Anemia Folate deficiency is a common nutritional problem that can lead to folate deficiency anemia. Levomefolic acid is an effective treatment for this condition, as it boosts folate levels in the body, allowing it to produce more red blood cells. Patients with folate deficiency anemia may also benefit from a diet rich in folate-containing foods such as leafy greens, beans, and fortified cereals. 2. Pregnancy and Prenatal Care Levomefolic acid is a crucial nutrient for pregnant women and women who are planning to conceive. Supplementing with levomefolic acid during pregnancy can help prevent neural tube defects (NTDs) in the developing fetus. NTDs are severe birth defects that affect the brain and spinal cord, which can lead to life-long disabilities or death. Levomefolic acid is often included in prenatal vitamins to ensure that women get enough of this critical nutrient. 3. Depression Methylation disorders, such as deficiencies in levomefolic acid, have been linked to various psychiatric disorders, including depression. Although not all cases of depression are related to methylation disorders, supplementing with levomefolic acid has shown promise in improving symptoms in some patients. Levomefolic acid may help boost the production of neurotransmitters like serotonin, which can help alleviate depression symptoms. 4. MTHFR Gene Mutation Levomefolic acid is often used as a treatment for MTHFR gene mutations. The MTHFR gene is responsible for the production of the MTHFR enzyme, which is essential for methylation. Mutations in this gene can lead to lower levels of the MTHFR enzyme, which can cause methylation disorders. Levomefolic acid can help alleviate symptoms related to MTHFR gene mutations by bypassing the need for the MTHFR enzyme to metabolize folic acid. 5. Cardiovascular Health Levomefolic acid may have a role in promoting cardiovascular health. Some studies have shown that supplementing with levomefolic acid can help lower homocysteine levels in the blood. Homocysteine is an amino acid that has been linked to an increased risk of cardiovascular disease. By lowering homocysteine levels, levomefolic acid may help reduce the risk of heart disease, stroke, and other cardiovascular problems. 6. Cancer Prevention Levomefolic acid may have a role in cancer prevention. Methylation disorders have been linked to an increased risk of cancer. By improving methylation processes, levomefolic acid may help reduce the risk of developing certain types of cancer. However, more research is needed in this area to determine the optimal dosage and duration of levomefolic acid supplementation and its effectiveness in cancer prevention. 7. Age-Related Cognitive Decline Levomefolic acid may also be useful in preventing age-related cognitive decline. As we age, many metabolic processes, including methylation, become less efficient. This can lead to memory loss, decreased cognitive function, and other neurological problems. Supplementing with levomefolic acid may help improve methylation in the brain, which can help protect against age-related cognitive decline. |
| Application |
| It is commonly used as a dietary supplement to prevent and treat folate deficiencies and has been shown to have many health benefits. |
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