Customization: | Available |
---|---|
Varieties: | Parasite Disease Prevention Medicine |
Component: | Animal |
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Name | Ivermectin | MF | C48H74O14 |
Appearance: White or yellowish-white crystalline powder
Empirical Formula: C48H74O14
Molecular Weight: 875.09
Melting point: 154.5~157°C
Ivermectin is widely used in cattle, sheep, horses, pigs, gastrointestinal nematodes, lung nematodes and parasitic arthropod, canine intestinal nematodes, ear mites, scabies mites, silk worm and microfilariae, gastrointestinal nematodes and external parasites and poultry. This product belong to the broad-spectrum drug resistant parasites.
Ivermectin for a variety of most of the life cycle of nematodes (but not all nematodes) role; For dish tail filarial microfilariae effectively, but for adult worms; For only in intestinal fecal round worms are also effective.
Ivermectin has the selective inhibitory effect, with no spinal nerve cells and muscle cells in the animal glutamic acid chlorine ion channels of the valve is the high binding affinity, leading to the proliferation of the chloride ion permeability of cell membrane, cause nerve cells or muscle cells hyperpolarization, parasites paralysis or death.
Item |
Specification
|
Description |
White crystalline powder |
Specific Rotation |
(-17°~-19°) |
Identification (1) Infra-red Spectrum
(2) High Performance Liquid Chromatography |
Infra-red spectrum of the sample should correspond to that of the reference standard The chromatogram of the Assay preparation exhibits major peaks for component, the retention times of which correspond to this exhibited in the chromatogram of the standard preparation |
Appearance of solution |
The solution is clear and not more intensely coloured than reference solution BY |
Water |
<1.0% |
Solphate Ash |
≤0.1% |
Heavy Metals |
≤20ppm |
Limit of Alcohol |
<5.0% |
Limit of Formamide |
<3.0% |
Limit of Methanol |
≤3000ppm |
Limit of Toluene |
≤890ppm |
Related Substance Impurities at RRT 1.3 to 1.5 Individual of all other impurities Total impurities |
≤2.5% ≤1% ≤5% |
Assay |
95.0%-102.0% |