Veterinary Medicine Powder CAS 55268-74-1 Praziquantel

• Powder: Yes
• Customized: Customized
• Certification: GMP, HSE, ISO 9001, USP, BP
• Suitable for: Adult
• State: Solid
• Purity: >98%
• Model NO.: Praziquantel
• Name: Praziquantel
• Mf: C19h24n2o2
• CAS: 55268-74-1
• Transport Package: Drum
• Specification: 99%
• Trademark: HS
• Origin: China
• HS Code: 2904201000
• Production Capacity: 100000

Product Description

Product Name: Praziquantel
Synonyms: 1-a]-isoquinolin-4-one,2-(cyclohexylcarbonyl)-1,2,3,6,7,11b-hexahydro-4H-pyrazino-[2;2-cyclohexylcarbonyl-1,2,3,6,7,11b-hexahydro-4h-pyrazino(2,1-a)isoquinolin-4;4h-pyrazino(2,1-a)isoquinolin-4-one,2-(cyclohexylcarbonyl)-1,2,3,6,7,11b-hexah;4H-pyrazino-[2,1-a]-isoquinolin-4-one,2-(cyclohexylcarbonyl)-1,2,3,6,7,11b-hexahydro-;biltricide;droncit;Praziquantel for system suitability;2-(Cyclohexanecarbonyl)-1,3,4,6,7,11b-hexahydro-4H-pyrazino[2,1-α]isoquinolin-4-one
CAS: 55268-74-1
MF: C19H24N2O2
MW: 312.41
EINECS: 259-559-6

Melting point: 136-138°C
Boiling point: 1377ºC
Density: 1.1209
Storage temp.: −20°C
Appearance: White Powder
Praziquantel (PZQ) is an isoquinoline derivative with most of the biological activity found in the levo enantiomer. The compound has no activity against nematodes, but it is highly effective against cestodes and trematodes.
 

Function:
(1) Praziquantel has a particularly dramatic effect on patients with schistosomiasis. Studies of those treated have shown that within six months of receiving a dose of praziquantel.

(2) Praziquantel is an anthelmintic or anti-worm medication. It prevents newly hatched insect larvae (worms) from growing or multiplying in your body.

(3) Praziquantel is also used to treat infection with liver flukes, caused by a type of worm found in East Asia. This worm enters the body while eating contaminated fish.
Praziquantel (Biltricide) is an anthelmintic effective against flatworms. Praziquantel is on the World Health Organization's List of Essential Medicines,a list of the most important medications needed in a basic health system. Praziquantel is not licensed for use in humans in the UK;it is,however,available as a veterinary anthelmintic,and is available for use in humans on a named-patient basis.

TESTS	SPECIFICATIONS&LIMITS	RESULTS
Characters	White or white crystalline powder	Complies
Solubility	slightly soluble in water, freely soluble in	Complies
	alcohol and in chloroform
Identification	IR: Corresponding to Praziquantel CRS	Positive
Melting Range	136°C~142°C	137.8~139.5°C
Heavy metals	Not more than 0.002%	<0.002%
Phosphate	Not more than 0.05%	<0.05%
Loss on drying	Not more than 0.5%	0.24%
Residue on ignition	Not more than 0.1%	0.03%
	Related compound A: not more than 0.2%	A: 0.09%
Related Substances	Related compound B: not more than 0.2%	B: 0.11%
	Related compound C: not more than 0.2%	C:Not detectable
Assay	98.5%~101.0% (dried basis)	99.38%
Particle size		20% less than 10um
		97% less than 50um
Residual Solvents	Limit of chloroform: NMT 60 ppm	NMT 60 ppm
	Limit of acetone: NMT 500 ppm	NMT 500 ppm
Conclusion	Conform with USP32