Cas:30516-87-1 Zidovudine powder
| product name |
Zidovudine |
| cas number |
30516-87-1 |
| apperance |
White powder |
| Density |
/ |
| MF |
C10H13N5O4 |
| MW |
267.241 |
Zidovudine is an antiviral drug with a chemical formula of C10H13N5O4, used for the treatment of AIDS or AIDS-related syndromes and immunodeficiency virus (HIV) infection. On March 19, 1987, the US Food and Drug Administration approved the drug for marketing. Zidovudine is the world's first anti-AIDS drug approved by the US FDA. Because of its definite curative effect, it has become the most basic component of "cocktail" therapy. It is highly active against retroviruses including human immunodeficiency virus (HIV) in vitro. In virus-infected cells, it is phosphorylated by cellular thymidine kinase to zidovudine triphosphate, which can selectively inhibit HIV reverse transcriptase, leading to the termination of HIV chain synthesis and preventing HIV replication.
Pharmacological action
This product is an antiviral drug, which is highly active against retroviruses including human immunodeficiency virus (HIV) in vitro. In virus-infected cells, it is phosphorylated by cellular thymidine kinase to zidovudine triphosphate, which can selectively inhibit HIV reversal enzyme, leading to the termination of HIV chain synthesis and preventing HIV replication.
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