Customization: | Available |
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Powder: | Yes |
Customized: | Customized |
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Product Name: | Vancomycin |
CAS: | 1404-90-6 |
MF: | C66H76Cl3N9O24 |
MW: | 1485.71 |
EINECS: | 215-772-6 |
Vancomycin as a narrow-spectrum antibiotics, only the gram positive bacteria effectively, such as hemolytic streptococcus, pneumococcus and enterococcus are sensitive to the bacteria resistant s. aureus is particularly sensitive to this product.Its mechanism of action is inhibition of the synthesis of bacterial cell walls, it mainly and the combination of bacterial cell walls, and make some sugar peptide amino acid could not enter the cell wall.Clinical is mainly used for resistance to penicillin severe infections caused by s. aureus bacteria, such as pneumonia, endocarditis and sepsis, infection and sepsis caused by hemolytic streptococcus, etc. Also has good curative effect.
This drug is used for serious gram-positive bacteria infection, especially for other antibiotic resistance or poor effects of methicillin-resistant staphylococcus aureus and epidermis staphylococcus aureus, enterococcus caused by severe infection (e.g., endocarditis, meningitis, meningitis, pneumonia, sepsis, or soft tissue infection, etc.);Also used for beta lactam class of antibiotics allergy the serious infection
Test | Specification | Results | |
Characteristics | A white or almost white powder | Conform | |
Identification | Infrared absorption | Conform | |
Chromatographic purity | Vancomycin B | ≥88.0% | 93.9% |
Any peak other than the main peak | ≤4.0% | 1.0% | |
monodechlorovancomycin | ≤4.7% | 1.5% | |
Water | ≤5.0%(W.F.) | 2.4% | |
Bacterial endotoxins | <0.25EU/mg | <0.25EU/mg | |
Potency(dried substance) | ≤925ug/mg | 1120ug/mg | |
Particulate matter | Conform | Conform | |
Heavy metals | ≤0.003% | <0.003% | |
Sterility | Conform | Conform | |
Clarity | Conform | Conform | |
Residual solvents | Ethanol≤5000ppm | 63ppm | |
Conclusion | The specification conform to USP35 |