CAS 2364-75-2 Mexidol Emoxypine Metformin

• Powder: Yes
• Customized: Customized
• Certification: GMP, ISO 9001, USP, BP
• Suitable for: Adult
• State: Solid
• Purity: >98%
• Model NO.: Emoxypine
• Name: Metformin HCl
• CAS: 657-24-9
• Mf: C4h11n5
• Transport Package: Drum
• Specification: 99%
• Trademark: HS
• Origin: China
• HS Code: 2904201000
• Production Capacity: 100000

Product Description

Metformin is the first-line medication for the treatment of type 2 diabetes.This is particularly true in people who are overweight. It is also used in the treatment of polycystic ovary syndrome.Limited evidence suggests metformin may prevent the cardiovascular disease and cancer complications of diabetes.It is not associated with weight gain.It is taken by mouth.     

For mild diabetes. It is mainly used for non-insulin-dependent diabetes mellitus, in which obese patients can be used as the drug of choice, and insulin-dependent diabetes mellitus can also be used in combination with insulin. It is effective in cases where certain sulfonylureas are ineffective.

This product is a biguanide oral hypoglycemic agent. It has a variety of mechanisms of action, including delaying the uptake of glucose from the gastrointestinal tract, increasing the utilization of peripheral glucose by increasing the sensitivity of insulin, and inhibiting excessive gluconeogenesis of the liver and kidney. This product does not reduce blood sugar levels in non-diabetic patients. During the patient's medication, the body weight is usually reduced, plasma cholesterol, triglyceride and pre-beta lipoprotein levels are reduced, and peripheral glucose metabolism can be improved.

 

Fuction&Application of Metformin

1. Increase the sensibility of surrounding tissues to insulin and the insulin-mediated usage of amylaceum.

2. Increase the the amylaceum usage to those organization which are not dependant on insulin, such as brain, blood corpuscle, medulla renis, intestinal tract, skin and so on.

3.  Restrain the heteroplasia of hepatic glycogen, lower the output of hepatic glycogen.

4. Restrain the intestinal wall cells from absorbing amylaceum.

5. Restrain the biosynthesis and storage of cholesterol, lower triglyceride, and total level of cholesterol.

Different from the function of insulin, it has no effect on promoting the combination of fat, no evident action of regulating blood sugar level to those who are normal, it usually causes no hypoglycemia action when used as the only medicine to II Diabetes.

 

Metformin HCL is a medication that is often prescribed to treat diabetes. It is used for decreasing blood sugar levels in people with type 2 diabetes.

Metformin HCL is an abbreviation for metformin hydrochloride.

The medication works in several ways. It reduces the amount of sugar made by the liver, limits the amount of sugar absorbed into the body from the diet, and makes insulin receptors more sensitive (helping the body respond better to its own insulin). All of these effects cause a decrease in blood sugar levels.

Metformin HCL is typically taken one to three times a day and comes in several forms and strengths. It comes in tablet form, two different long-acting forms, and a liquid version.

Item	Specifications (USP)	Specifications (AJI)
Description	White crystals or crystalline powder	White crystals or crystalline powder
Identification	Infrared absorption spectrum	Infrared absorption spectrum
Specific rotation	+26.3 °- +27.7°	+26.9 °- +27.9°
[a]D20°
State of solution	---	≥ 98.0%
/Transmittance
Chloride (Cl)	≤ 0.05%	≤ 0.020%
Ammonium (NH4)	---	≤ 0.02%
Sulfate (SO4)	≤ 0.03%	≤ 0.020%
Iron (Fe)	≤ 0.003%	≤ 10PPm
Heavy metals (Pb)	≤ 0.0015%	≤ 10PPm
Arsenic (As2O3)	---	≤ 1PPm
Other amino acids	---	Chromatographically not detectable
Loss on drying	≤ 0.5%	≤ 0.5%
Residue on ignition	≤ 0.3%	≤ 0.10%
(sulfated)
Assay	98.5-101.5%	99.0 - 101.0%
PH	---	10.5-12.0
Organic volatile impurities	Meets the requirements	---