Customization: | Available |
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Powder: | Yes |
Customized: | Customized |
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Fuction&Application of Metformin
1. Increase the sensibility of surrounding tissues to insulin and the insulin-mediated usage of amylaceum.
2. Increase the the amylaceum usage to those organization which are not dependant on insulin, such as brain, blood corpuscle, medulla renis, intestinal tract, skin and so on.
3. Restrain the heteroplasia of hepatic glycogen, lower the output of hepatic glycogen.
4. Restrain the intestinal wall cells from absorbing amylaceum.
5. Restrain the biosynthesis and storage of cholesterol, lower triglyceride, and total level of cholesterol.
Different from the function of insulin, it has no effect on promoting the combination of fat, no evident action of regulating blood sugar level to those who are normal, it usually causes no hypoglycemia action when used as the only medicine to II Diabetes.
Metformin HCL is a medication that is often prescribed to treat diabetes. It is used for decreasing blood sugar levels in people with type 2 diabetes.
Metformin HCL is an abbreviation for metformin hydrochloride.
The medication works in several ways. It reduces the amount of sugar made by the liver, limits the amount of sugar absorbed into the body from the diet, and makes insulin receptors more sensitive (helping the body respond better to its own insulin). All of these effects cause a decrease in blood sugar levels.
Metformin HCL is typically taken one to three times a day and comes in several forms and strengths. It comes in tablet form, two different long-acting forms, and a liquid version.
Item |
Specifications (USP) |
Specifications (AJI) |
Description |
White crystals or crystalline powder |
White crystals or crystalline powder |
Identification |
Infrared absorption spectrum |
Infrared absorption spectrum |
Specific rotation |
+26.3 °- +27.7° |
+26.9 °- +27.9° |
[a]D20° |
||
State of solution |
--- |
≥ 98.0% |
/Transmittance |
||
Chloride (Cl) |
≤ 0.05% |
≤ 0.020% |
Ammonium (NH4) |
--- |
≤ 0.02% |
Sulfate (SO4) |
≤ 0.03% |
≤ 0.020% |
Iron (Fe) |
≤ 0.003% |
≤ 10PPm |
Heavy metals (Pb) |
≤ 0.0015% |
≤ 10PPm |
Arsenic (As2O3) |
--- |
≤ 1PPm |
Other amino acids |
--- |
Chromatographically not detectable |
Loss on drying |
≤ 0.5% |
≤ 0.5% |
Residue on ignition |
≤ 0.3% |
≤ 0.10% |
(sulfated) |
||
Assay |
98.5-101.5% |
99.0 - 101.0% |
PH |
--- |
10.5-12.0 |
Organic volatile impurities |
Meets the requirements |
--- |