| Customization: | Available |
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| Powder: | Yes |
| Customized: | Customized |
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Name : Sodium dichloroacetate
Shape : White crystalline powder
Sodium dichloroacetate (DCA) is a mitochondrial pyruvate dehydrogenase kinase inhibitor, and is an orally absorbable small molecular compound for MELAS syndrome, and children with congenital lactic acidosis and other diseases that are treated in the clinic. Recent studies had found that DCA acts as a potential vasoprotective agent by inhibiting PDK2 and reducing coronary endarterium proliferation. Further, DCA promotes brain regeneration after cerebral ischemia, which indicates that DCA might play an important role in VD.
DCA acts as an inhibitor of cell growth in vivo and in vitro without causing programmed cell death (apoptosis).DCA is a safe drug with no toxicity to the heart, lungs, kidneys or bone marrow.The most serious side effects include peripheral neuropathy, which is reversible.DCA has anticancer activity in several cancer types, including colon, prostate, ovarian, neuroblastoma, lung, cervical, endometrial, cholangiocarcinoma, sarcoma, and T-cell lymphoma.
| Name | CAS | molecular | density |
| Sodium dichloroacetate | 2156-56-1 | C2HCl2NaO2 | 1.081 |
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