CAS 71686-01-6 Supplement Ingredients Calcium Alpha Ketoglutarate Ca Akg

• Customization: Available
• CAS No.: 71686-01-6
• Formula: C5h6o5
• Model NO.: Calcium Alpha-Ketoglutarate
• EINECS: /
• Type: Pharmaceutical Intermediates
• Appearance: Powder
• Quality: Refined
• Colour: White
• Name: Alpha Ketoglutaric Acid Powder
• Mf: C5h4cao5•H2O
• CAS: 71686-01-6
• MOQ: 1kg
• Transport Package: Sea
• Specification: 99%
• Trademark: HS
• Origin: China
• HS Code: 2904201000
• Production Capacity: 100000

Product Description

CAS 71686-01-6 Supplement Ingredients Calcium Alpha Ketoglutarate Ca Akg

Other Name	ALPHA-KETOGLUTARATE CALCIUM
Assay	99%
Apprearance	White crystalline powder
Package	1kg/carton; 25kg/drum
Payment	Alipay; Western Union; TT
Shipment	DHL; FedEx, EMS; Air; Sea
Standard	USP/EP/CP/BP
Storage	Sealed in dark and dry place
Shelf Life	2 Years

 
 
I. Chemical Structure and Properties \
Alpha-Ketoglutaric acid AKG
1. Structural Characteristics   - It is an α - keto acid, and its chemical name is 2 - oxoglutaric acid. Its chemical formula is C5H6O5.
2. Physical Properties   - It is usually a white crystalline or crystalline powder. It is soluble in water, slightly soluble in ethanol, and insoluble in ether. It has a certain acidity because the carboxyl group in its molecule can ionize hydrogen ions.
II. Role in Organisms
1. Role in the Tricarboxylic Acid Cycle (TCA Cycle)   - In the aerobic metabolism process of cell respiration, α - ketoglutaric acid is a key intermediate product of the tricarboxylic acid cycle. It is generated by the oxidative decarboxylation of isocitric acid under the action of isocitrate dehydrogenase. Then, α - ketoglutaric acid continues to participate in subsequent reactions and undergoes oxidative decarboxylation reaction catalyzed by the α - ketoglutarate dehydrogenase complex to generate succinyl - CoA. This process produces reduced coenzyme I (NADH) and carbon dioxide. NADH can enter the electron transport chain to produce ATP (adenosine triphosphate).   - For example, in the mitochondria of the human body, the TCA cycle is constantly operating, and α - ketoglutaric acid is like a "transfer station", promoting the process of energy metabolism and providing energy for cells.
2. Amino Acid Metabolism   - α - ketoglutaric acid is also very important in the synthesis and catabolism of amino acids. It can be interconverted with some amino acids through transamination. For example, a reversible transamination reaction can be catalyzed by glutamate dehydrogenase between glutamate and α - ketoglutaric acid. In this reaction, glutamate loses an amino group and becomes α - ketoglutaric acid, and at the same time, α - ketoglutaric acid gains an amino group to generate glutamate, which plays a key role in maintaining the balance of amino acids in the body.
3. Association with Other Metabolic Pathways   - It is also related to some other metabolic pathways. For example, in the process of glutamine synthesis, α - ketoglutaric acid can participate as a raw material. In some tissues, glutamine synthetase uses glutamate and ammonium ions and consumes α - ketoglutaric acid to synthesize glutamine, which is of great significance for the transport and metabolism of amnia.

ltem	Specification	Result	Method
Assay	>99.00%	99.50%	HPLC
B1Afatoxin B1	≤5.0ppb	Conforms	LCMS
Appearance	Fine Powder	Conforms	Organoleptic
Color	White Powder	Conforms	Organoleptic
Odor&Taste	Characteristic	Conforms	Organoleptic
Physical&chemical Characteristics
Particle Size	95%Through 80 mesh	Conforms	Sieving
Loss on Drying	≤5.0%	3.80%	USP<731>
Ash	≤5.0%	3.20%	USP<561>
Loose Density	Actual Value	0.51g/'ml	USP<616>
Tight Density	Actual Value	3.20%	USP<616>
Residual Solvents	Actual Value	0.51g/ml	USP<467>
Pesticide Residue	Actual Value	0.69g'ml	USP<561>
Heavy Metals	≤10ppm	Conforms	USP<231>
Lead(Pb)	≤1.0ppm	Conforms	USP<730>
Anic(As)	≤1.0ppm	Conforms	USP<730>
Mery(Hg)	≤0.1ppm	Conforms	USP<730>
Caum(Cd)	≤1.0ppm	Conforms	USP<730>
MicrobiologicalTests
Total plate Count	<5000cfu/g	Conforms	USP<2021>
Ycast& Mold	≤100cfu/g	Conforms	USP<2021>
E.Coli.	Negative	Negative	USP<2022>
Salmonella	Negative	Negative	USP<2022>
Staphylococcus	Negative	Negative	USP<2022>
Conclusion	Confomm to In-house standard