| Customization: | Available |
|---|---|
| Powder: | Yes |
| Customized: | Customized |
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| Production name | Praziquantel |
| CAS NO. | 55268-74-1 |
| MF | C19H24N2O2 |
| MW | 312.406 |
| Appearance | White crystalline powder |
Praziquantel (Biltricide) is an anthelmintic effective against flatworms. Praziquantel is not licensed for use in humans in the UK; it is, however, available as a veterinary anthelmintic, and is available for use in humans on a named-patient basis.
It is on the World Health Organization's List of Essential Medicines, a list of the most important medications needed in a basic health system.
(1) Praziquantel has a particularly dramatic effect on patients with schistosomiasis. Studies of those treated have shown that within six months of receiving a dose of praziquantel, up to 90% of the damage done to internal organs due to schistosomiasis infection can be reversed.
(2) Praziquantel is an anthelmintic or anti-worm medication. It prevents newly hatched insect larvae (worms) from growing or multiplying in your body.
(3) Praziquantel is used to treat infections caused by Schistosoma worms, which enter the body through skin that has come into contact with contaminated water.
(4) Praziquantel is also used to treat infection with liver flukes, caused by a type of worm found in East Asia. This worm enters the body while eating contaminated fish.
| TESTS | SPECIFICATIONS&LIMITS | RESULTS |
| Characters | White or white crystalline powder | Complies |
| Solubility | slightly soluble in water, freely soluble in alcohol | Complies |
| Identification | IR: Corresponding to Praziquantel CRS | Positive |
| Melting Range | 136°C~142°C | 137.8~139.5°C |
| Heavy metals | Not more than 0.002% | <0.002% |
| Phosphate | Not more than 0.05% | <0.05% |
| Loss on drying | Not more than 0.5% | 0.24% |
| Residue on ignition | Not more than 0.1% | 0.03% |
| Related compound A: not more than 0.2% | A: 0.09% | |
| Related Substances | Related compound B: not more than 0.2% | B: 0.11% |
| Related compound C: not more than 0.2% | C:Not detectable | |
| Assay | 98.5%~101.0% (dried basis) | 99.38% |
| Particle size | 20% less than 10um | |
| 97% less than 50um | ||
| Residual Solvents | NMT 60 ppm | NMT 60 ppm |
| Conclusion | Conform with USP32 | |
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