CAS 136-47-0 Hydrochloride HCl lidocaine procaine Tetracaine 
| Product Name |
Tetracaine Hydrochloride |
CAS |
136-47-0 |
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Standard: USP
Level: Pharaceutical grade
Content: 99%
Appearance: white powder
Packing: 25/ cardboard drum detachable
Physical and chemical properties: white crystal or crystalline powder; odorless, slightly bitter taste, numb tongue. This product is soluble in water and soluble in ethanol.
Application: Local anesthesia is stronger than procaine, and it is also more toxic. It can penetrate the mucous membrane and is mainly used for mucosal anesthesia.
Tetracaine specification:
Tetracaine HCL is synthesized from 4-butylaminobenzoic acid. The ethyl ester is formed through an acid-catalyzed esterification reaction. Base-catalyzed transesterification is achieved by boiling the ethyl ester of 4-butylaminobenzoic acid with excess 2-dimethylaminoethanol in the presence of a small amount of sodium ethoxide.
Tetracaine, also known as Amethocalne, Dlcalne, Pontocaine, Decicaine, is a kind of Local Anesthetic. It is highly soluable in Non-polar solvent, and combines with Plasma protein by 85%.
Tetracaine takes effect very fast. It just needs 1-2 min. Usually, its half life is 5-10 min. And it can lasts for 20 ~ 40min.
It is widely used as pain-killer in Mucosal surface anesthesia, Conduction anesthesia, Epidural anesthesia, Spinal anesthesia, Ophthalmic topical anesthesia and so on.
Tetracaine is more efficient than Procaine. It is 10-15 times more effective than it.
Tetracaine Application
Tetracaine (INN, also known as amethocaine; trade name Pontocaine. Ametop and Dicaine) is a potent local anesthetic of the ester group. It is mainly used topically in ophthalmology and as an antipruritic, and it has been used in spinal anesthesia.
In biomedical research, tetracaine is used to alter the function of calcium release channels (ryanodine receptors) that control the release of calcium from intracellular stores. Tetracaine is an allosteric blocker of channel function. At low concentrations, tetracaine causes an initial inhibition of spontaneous calcium release events, while at high concentrations, tetracaine blocks release completely
Tetracaine hydrochloride Packaging & Delivery:
25kg drum /1kg bag /2kg bag /5kg bag
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| Product name |
Tetracaine Hcl |
| CAS No. |
136-47-0 |
Outer Packing |
25KG |
| Production date |
2018-11-30 |
Shelf life |
2020-11-29 |
| Standard adopted |
USP40 |
| Items of analysis |
Specification |
Results |
| Description |
A white,crystalline power |
white,crystalline power |
| Identification |
Easily soluble in water, soluble in ethanol, insoluble in ether and benzene |
Complies |
| Identification |
retention time consistent with the determination under |
Complies |
| Identification |
hould identify significant chloride reaction |
Complies |
| Water |
≤2.0% |
0.23% |
| Melting range |
About 148ºC |
148.8ºC~150.2ºC |
| Resiue on ignition |
≤0.1% |
0.034% |
| Related Substances |
Complies |
Complies |
| Ethanol |
≤0.5% |
0.055% |
| Acetone |
≤0.5% |
Not detected |
| Methylbenzene |
≤.089% |
Not detected |
| Assay |
98%~101.0% |
99.7% |
| Conclusion |
Qualified |
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