GMP Pharmaceutical Raw Materials Neomycin Sulphate
Name : Phytosterol
Shape : White to quasi-white powder
Use for : Poor oral absorption requires intravenous administration.After intravenous injection, it was rapidly distributed to tissues throughout the body.Among them, liver and kidney concentration is the highest, concentrated in the nucleated cells, the content is higher in the white blood cells, the product is not easy to pass through the brain barrier, so it does not enter the cerebrospinal fluid: the product metabolism is very little, within 24 hours 12% ~ 25% from the kidney, 50% ~ 90% from the bile discharge.Due to the slow release of the product from the storage tissue, the plasma elimination half-life is long, about 36h
Neomycin is an antibiotic belonging to the aminoglycoside class of antibiotics with streptomycin, kanamycin, and gentamicin.It's produced by Streptomyces freund;Effective against both Gram-positive and Gram-negative bacteria, the product is mainly a mixture of neomycin B and C.Neomycin had complete cross - resistance to kanamycin and partial cross - resistance to streptomycin.Similar to similar antibiotics, it is nephrotoxic and endototoxic, and the damage to the inner ear is often irreversible .
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