Antihistamine Powder Chlorphenamine Maleate

• Powder: Yes
• Customized: Customized
• Certification: GMP, ISO 9001, USP, BP
• State: White Powder
• Purity: >99%
• CAS: 113-92-8
• Model NO.: chlorphenamine maleate
• Mf: C20h23cln2o4
• Einecs No.: 204-037-5
• Test Method: HPLC
• Melting Point: 130-135 C(Lit.)
• Shelf Life: 24 Months
• Storage: Cool Dry Place
• Transport Package: 1kg/Bag
• Specification: EP/BP/USP
• Trademark: HNB
• Origin: China
• Production Capacity: 2000kg/Month

Product Description

Product Name	Chlorpheniramine Maleate
Other Name	Chlorphenamine
CAS No.	113-92-8
Einecs No.	204-037-5
Appearance	White powder
Speccification	99%
Molecular formula	C20H23ClN2O4
MOQ	1kg
Application	Medicine

Chlorpheniramine Maleate is a small molecule H1-receptor antagonist. Increased ornithine decarboxylase activity induced in an ischemia-reperfusion state was attenuated by Chlorpheniramine Maleate, indicating that this increase is mediated through engagement of the H1-receptor by histamine. Histamine-mediated repair of intestinal mucosa following ischemiareperfusion was also demonstrated to operate through the H1-receptor with Chlorpheniramine Maleate. Induction of ornithine decarboxylase was blocked by Chlorpheniramine Maleate in Ehrlich carcinoma and MCF-7 cells. The positive inotropic effect of H1-receptor stimulation by histamine on protein tyrosine phosphorylation in guinea pig left atrium was antagonized by Chlorpheniramine Maleate.

 

 

Items	Standard	Result
Assay	98.0 ~102.0%	99.9%
Appearance	White or almost white powder	White Powder
Identification	Meets the requirements	Complies
Specific Rotation	-0.10 ~ +0.10°	Complies
Water	≤0.5%	0.06%
Heavy Metals	≤0.002%	Complies
Redidue in Ignition	≤0.2%	0.01%
Related Substances	Meets the requirements	Complies
Benzene Sulfonic Acid	27.3 ~ 28.7%	28.0%
Ethanol	≤300ppm	Complies
Benzene	≤2ppm	Complies
Acetic Acid	≤600ppm	Complies
Particle Size	Meets the requirements	Complies