CAS 23828-92-4 99% Ambroxol Hydrochloride, Ambroxol HCl

• CAS No.: 23828-92-4
• Formula: C13h19br2cln2o
• EINECS: 245-899-2
• Type: Pharmaceutical Intermediates
• Appearance: Light Yellow Powder
• Colour: Yellow
• Model NO.: Ambroxol HCL
• Mf: C13h19br2cln2o
• MW: 414.56
• Merck: 14, 386
• Shelf Life: 24 Months
• Storage: Cool Dry Place
• Grade: Medicine Grade
• Transport Package: 1kg/Bag, 25kg/Drum
• Specification: 99%
• Trademark: HNB
• Origin: China
• Production Capacity: 5000kg/Month

Product Description

Product Name	Ambroxol hydrochloride
Apperance	White powder
Specification	99%
Test Method	HPLC
Cas No.	23828-92-4
M.F.	C13H19Br2ClN2O
M.W	414.56
Soluble	Slightly soluble in water

Ambroxol Hcl is a secretolytic agent used in the treatment of respiratory diseases associated with viscid or excessive mucus. It is the active ingredient of Mucosolvan, Mucobrox, Lasolvan, Mucoangin, Surbronc and Lysopain. The substance is a mucoactive
drug with several properties including secretolytic and secretomotoric actions that restore the physiological clearance mechanisms of the respiratory tract, which play an important role in the body's natural defence mechanisms. It stimulates synthesis and release of surfactant by type II pneumocytes. Surfactants acts as an anti-glue factor by reducing the adhesion of mucus to the bronchial wall, in improving its transport and in providing protection against infection and irritating agents.

Function 
1. Cough medicine;
2. Antitussive and expectorant drugs, for acute and chronic respiratory diseases, especially chronic bronchitis expectorant treatment. Can promote the discharge of viscous secretions within the respiratory tract and reduce the retention of mucus, which significantly promote sputum. It is suitable for acute and chronic respiratory diseases accompanied by abnormal sputum secretion and expectoration dysfunction.
Ambroxol hydrochloride Application:
For acute and chronic bronchitis, bronchial asthma, bronchiectasis, tuberculosis and other sputum caused by viscous, sputum difficult.

Item	Specification
Appearance	White or yellowish crystalline powder
Appearance of solution	Not more intensely colored than the reference solutionY6
Melting point	235 ~ 240°C
Solubility	A) Water: sparingly soluble
	B) Methanol: soluble
	C) Methylene Chloride: practically insoluble
Identification	A) UV Absorption: 3.2 ~ 3.4
	B) IR Spectrum
	C) TLC
	D) Chlorides Test
Related substances	Individual impurity: 0.1% Max
	Total impurities: 0.3% Max
Heavy metals	20ppm Max
Loss on drying	Loss on drying
Sulfated ash	0.1% Max
PH (1% aqueous solution)	4.5 ~ 6.0
Assay	99.0 ~ 101.0%