Cas:55268-75-2 Cefuroxime powder
| product name |
Cefuroxime |
| cas number |
55268-75-2 |
| apperance |
white powder |
| Density |
1.8±0.1 g/cm3 |
| MF |
C16H16N4O8S |
| MW |
424.385 |
Cefuroxime, a second-generation cephalosporin, binds to penicillin binding proteins (PBPs) on the bacterial cell membrane to inhibit cell division and growth, and finally dissolve and die the bacteria. Cefuroxime has a broad-spectrum antibacterial effect and a wide range of applications. It can be used for respiratory infections, ear, nose, and throat infections, urinary tract infections, skin and soft tissue infections, bone and joint infections, gonorrhea, including sepsis and Other infections such as meninges.
Appearance and properties: white crystals, easily soluble in water or buffer solution, soluble in methanol, very slightly soluble in ethyl ethyl, ether, octanol, benzene or chloroform, the solubility in water is 500mg/2.5ml. pKa (water): 2.5; pKa (Z. methylformamide): 5.1. [α] D20 +60° (C=0.91, water).
Density: 1.76
Melting point: 171.5-173°C
Refractive index: 1.665
Suitable for moderate to severe infections caused by pathogenic bacteria that are sensitive to the product, producing or not producing lactamase, lower respiratory tract infections, acute attacks of pneumonia, chronic bronchitis, acute bronchitis, lung abscesses and other lung infections; urinary system infections , Acute nephritis, acute exacerbation of chronic nephritis, complicated urinary tract infections, abdominal infections, peritonitis, cholecystitis, cholangitis and other intra-abdominal infections, pelvic infections, pelvic inflammatory disease and other infections. Sepsis, meningitis, skin and soft tissue infections.
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