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Sodium cromoglicate, also known as disodium cromoglicate, has a good preventive and therapeutic effect on immediate allergic reactions. Its mechanism of action is to stabilize the cell membrane of mast cells, prevent mast cells from degranulation, thereby inhibiting the release of allergic reaction mediators such as histamine, serotonin, and slow-reacting substances, thereby inhibiting the adverse effects of allergic reaction mediators on tissues. Its effect of inhibiting the release of allergic reaction mediators may be by inhibiting intracellular cyclic phosphoryl glycoside phosphodiesterase, resulting in an increase in the concentration of intracellular cyclic phosphoryl glycosides (cAMP), preventing calcium ions from being transported into mast cells, thereby stabilizing hypertrophy The cell membrane prevents the release of allergic reaction mediators.
English name: Sodium cromoglicate CAS Number: 15826-37-6 Molecular formula: C23H14O11.2Na Molecular weight: 512.33 EINECS number: 239-926-7 Appearance: White fine powder |