CAS 871700-17-3 Factory Supply High Purity Trametinib
What is Trametinib?
Trametinib is an anti-cancer drug. It is a MEK inhibitor drug with anticancer activity. It inhibits MEK1 and MEK2. Trametinib has a good effect on metastatic melanoma with BRAF V600E mutation in a phase III clinical trial. In this mutation, the amino acid valine (V) at position 600 in the BRAF protein has been replaced by glutamic acid, making the mutant BRAF protein constitutively active.
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